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Respiratory diseases impose an immense worldwide health burden. Traditional high resolution computed tomography is regarded as the gold standard for structural lung imaging but does not routinely provide functional information due to cardiac and respiratory motion artifact. We aim to develop and evaluate a low-dose dynamic CT technique with temporal resolution as fast as 66 ms for airway imaging using a dual-source photon-counting-detector (PCD)-CT. An inflatable pig lung phantom that can simulate respiratory cycle was used. On the back of the phantom small spheres with different radius were attached for quantification. Phantom was imaged with two scanning modes, a dual-source prospectively gated adaptive sequential mode with slow (30 bpm) electrocardiogram (ECG) signal and standard dynamic cine mode on a PCD-CT. Motion artifacts were reduced on images acquired from slow ECG-gated dynamic images compared to traditional cine. Improved temporal resolution led to more accurate quantitative measurements. Compared to standard dynamic CT the proposed slow ECG-gated dynamic imaging on PCD-CT can achieve a better temporal resolution, reduces motion artifacts and improves quantification.
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Jelena Mihailovic, Michael Bruesewitz, Nathan Hull, Nadir Demirel, Cynthia McCollough, Lifeng Yu, "High-temporal-resolution dynamic imaging of airways in photon-counting-detector CT," Proc. SPIE 12925, Medical Imaging 2024: Physics of Medical Imaging, 129251G (3 April 2024); https://doi.org/10.1117/12.3008732