Mid-infrared photothermal (MIP) microscopy is an advanced type of infrared (IR) spectroscopy that surpasses conventional IR microscopy in terms of sensitivity and spatial resolution. Rapid progress on this field has revealed the excellent applicability of MIP microscopy in super-resolution IR imagings of polymer surfaces to bio-materials. Nonetheless, further improving the MIP performance would open the possibility of analyzing chemicals in a new analytical system. In light of this, we have been actively investigating the use of colloidal plasmonic nanowires in MIP microscopy to enhance performance. High crystalline, wet-synthesized colloidal metallic nanowires with several nm in length show strong resonance with mid-IR laser light theough Fabry-Perot resonance, which reaults in a a resonant-surface-enhanced infrared absorption (SEIRA) effect. Utilizing the strong near-field light that is confined to the metallic nanowire, the enhanced MIP performance in terms of both spatial resolution and surface/detection sensitivity can be achieved in optical- and AFM-MIP microscopy. This invited talk will feature an update on the latest progress made on this topic.
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