Antibody-based fiber optic sensors for environmental and process-control applications

Steven M. Barnard; David R. Walt

doi:10.1117/12.24800

1 March 1991 Antibody-based fiber optic sensors for environmental and process-control applications

Steven M. Barnard, David R. Walt

Proceedings Volume 1368, Chemical, Biochemical, and Environmental Fiber Sensors II; (1991) https://doi.org/10.1117/12.24800
Event: SPIE Microelectronic Interconnect and Integrated Processing Symposium, 1990, San Jose, United States

Abstract

Combining fluoroimmunoassay principles and fiber-optic fluorimetry has extended the available transduction schemes for development of fiber-optic sensors. Three representative designs are discussed focusing on a sensor configuration utilizing a controlled-release polymer to sustain a release of indicating reagents over long periods. This novel approach has been adapted for pesticide monitoring. A model system has been designed that releases the reagents of a homogeneous fluoroimmunoassay from an ethylene vinyl acetate polymer for the detection of atrazine. The sensor utilizes a competition reaction between fluorescent-labeled and unlabeled atrazine for the available binding sites on labeled anti-atrazine antibodies.

Citation Download Citation

Steven M. Barnard and David R. Walt "Antibody-based fiber optic sensors for environmental and process-control applications", Proc. SPIE 1368, Chemical, Biochemical, and Environmental Fiber Sensors II, (1 March 1991); https://doi.org/10.1117/12.24800

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