Determination of the optical penetration depth in tumors from biopsy samples

P. Lenz

doi:10.1117/12.48215

1 November 1991 Determination of the optical penetration depth in tumors from biopsy samples

P. Lenz

Proceedings Volume 1525, Future Trends in Biomedical Applications of Lasers; (1991) https://doi.org/10.1117/12.48215
Event: MedTech '91, 1991, Berlin, Germany

Abstract

This method is destined for use in connection with photochemotherapy. It consists of two steps: (1) Each tumor is characterized individually by two parameters which are obtained by goniometric measurement of the light crossing a small sample (1 mm3). These parameters can be easily determined in a clinical environment but provide no direct information on the light distribution in the bulk. (2) The above parameters are related with the effective penetration depth for geometries and wavelengths of practical relevance. The relationship is established experimentally by multiple measurements in phantoms which are composed so as to closely approach the optical properties of tumors.

Citation Download Citation

P. Lenz "Determination of the optical penetration depth in tumors from biopsy samples", Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); https://doi.org/10.1117/12.48215

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