Comparison of tissue ablation by ultrashort laser pulses in the nano-, pico-, and femtosecond range

Frieder H. Loesel; Peter Brockhaus; Joerg P. Fischer; Marcus H. Goetz; Frank Noack; Josef F. Bille

doi:10.1117/12.199201

18 January 1995 Comparison of tissue ablation by ultrashort laser pulses in the nano-, pico-, and femtosecond range

Frieder H. Loesel, Peter Brockhaus, Joerg P. Fischer, Marcus H. Goetz, Frank Noack, Josef F. Bille

Proceedings Volume 2323, Laser Interaction with Hard and Soft Tissue II; (1995) https://doi.org/10.1117/12.199201
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

Plasma mediated ablations of calf brain tissue and corneal tissue have been performed with ultrashort pulses provided by different laser systems: A 30 ps Nd:YLF amplified laser with up to 1.5 mJ of pulse energy and a powerful 180 fs Ti:Sapphire oscillator/regenerative amplifier laser system capable of pulse energies of up to 300 (mu) J. With the femtosecond pulses the threshold in energy density needed for initiating the ablation process was found to be significantly lower than with longer pulse durations. Furthermore, the amount of ablated material is by a factor of two greater with the femtosecond pulses compared to the results obtained with the picosecond pulses. Histological examinations did not show any thermal or structural damage in adjacent tissue with pulses in the pico- and femtosecond range as it could be found after irradiation with longer pulses. The morphology of the excisions is of a very high quality.

Citation Download Citation

Frieder H. Loesel, Peter Brockhaus, Joerg P. Fischer, Marcus H. Goetz, Frank Noack, and Josef F. Bille "Comparison of tissue ablation by ultrashort laser pulses in the nano-, pico-, and femtosecond range", Proc. SPIE 2323, Laser Interaction with Hard and Soft Tissue II, (18 January 1995); https://doi.org/10.1117/12.199201

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