Effect of refractive index and calibration factor on image reconstruction in optical tomography

Pieter van der Zee; Reem Khalaf; Laurence C. W. Dixon; Alan Davies

doi:10.1117/12.334373

30 December 1998 Effect of refractive index and calibration factor on image reconstruction in optical tomography

Pieter van der Zee, Reem Khalaf, Laurence C. W. Dixon, Alan Davies

Proceedings Volume 3566, Photon Propagation in Tissues IV; (1998) https://doi.org/10.1117/12.334373
Event: BiOS Europe '98, 1998, Stockholm, Sweden

Abstract

Results obtained with an experimental Optical Tomography system, using a frequency domain technique and a cylindrical geometry are presented. In particular, problems occurring in the reconstruction of Optical Tomography images due to uncertainties in the values for relative refractive index and system calibration factor have been investigated. It is shown that considerable errors can arise in the values for the reconstructed absorption and diffusion images as a result of these uncertainties, and that these uncertainties can give rise to artifacts in the reconstructed images. In addition, the degeneracy between the absorption coefficient, (mu) _a, and the diffusion coefficient, D, is shown for reconstruction from DC data, with the conclusion that for optimal reconstruction DC data cannot be discarded, and therefore an accurate system calibration remains a necessity.

Citation Download Citation

Pieter van der Zee, Reem Khalaf, Laurence C. W. Dixon, and Alan Davies "Effect of refractive index and calibration factor on image reconstruction in optical tomography", Proc. SPIE 3566, Photon Propagation in Tissues IV, (30 December 1998); https://doi.org/10.1117/12.334373

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