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We have developed an optical coherence tomographic system which uses a high power low-coherence laser source and a Michelson interferometer. A heterodyne detection method has been used for detecting feeble reflection from object. We discuss the application of this imaging system for neuron activities and in vivo imaging of tissues.
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Jiyuan Liu, Atsushi Miyawaki, "Development of an optical coherence tomographic system for imaging of tissue," Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); https://doi.org/10.1117/12.364389