Cytochrome oxidase reduction/oxidation charge-coupled monitor with large-area pickup optode

Frederick A. Kriedt; Cedric F. Walker; Harvey T. Swanson; Sheldon F. Gottlieb; Keith W. Van Meter

doi:10.1117/12.384952

8 May 2000 Cytochrome oxidase reduction/oxidation charge-coupled monitor with large-area pickup optode

Frederick A. Kriedt, Cedric F. Walker, Harvey T. Swanson, Sheldon F. Gottlieb, Keith W. Van Meter

Proceedings Volume 3918, Biomedical Spectroscopy: Vibrational Spectroscopy and Other Novel Techniques; (2000) https://doi.org/10.1117/12.384952
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

Except for amplitude, the near IR spectra recorded through intact scalp and skull were identical to those from brain surface recordings. Reduction of scattering due to hypoxia was clearly evident in nitrogen induced spectra. Absorbance peaks, hemoglobin and aa₃, were visible and did not seem to be affected by percentage of deoxyhemoglobin. The 600 nm peak is believed to be caused by scattering, not aa₃ absorbance. Work is continuing to further demonstrate the validity of the hemoglobin and aa₃ absorption peaks.

Citation Download Citation

Frederick A. Kriedt, Cedric F. Walker, Harvey T. Swanson, Sheldon F. Gottlieb, and Keith W. Van Meter "Cytochrome oxidase reduction/oxidation charge-coupled monitor with large-area pickup optode", Proc. SPIE 3918, Biomedical Spectroscopy: Vibrational Spectroscopy and Other Novel Techniques, (8 May 2000); https://doi.org/10.1117/12.384952

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