Laser correlation spectrometry: a new approach to organizing oncological screening for a population exposed to chronic irradiation

Alexander Akleyev; Igor Pashkov; Mikhail Kisselyov; Leonid A. Noskin

doi:10.1117/12.375274

30 December 1999 Laser correlation spectrometry: a new approach to organizing oncological screening for a population exposed to chronic irradiation

Alexander Akleyev, Igor Pashkov, Mikhail Kisselyov, Leonid A. Noskin

Author Affiliations +

Proceedings Volume 4059, Laser Use in Oncology II; (1999) https://doi.org/10.1117/12.375274
Event: Selected Papers on Laser Use in Oncology II, 1999, none, Armenia

Abstract

The issue of stochastic effects of radiation exposure (mostly leukemia and cancer), and early detection of malignant tumors, as a key aspect of the problem, is of crucial importance to the population chronically exposed due to the activities of the Mayak Production Association in the Urals region (Russia). Given the large number of exposed population, screening is considered to be the most expedient method to organize medical observation of exposed persons. As was shown by the results of medical examinations conducted for 1 391 residents of the Techa riverside villages, laser correlation spectrometry (LCS) of blood plasma has proved to be a highly effective screening method for early (pre-clinical) detection of malignant neoplasms and pre-cancerous conditions. It was established that LC- spectra of blood plasma in persons with cancer and pre- cancer can easily be differentiated from non-cancer conditions. Of particular diagnostic significance is the high-frequency range of the spectrum. The development of a diagnostic algorithm has allowed to carry out a computer- based classification of blood plasma LC spectra as a component of exposed population health monitoring system.

Citation Download Citation

Alexander Akleyev, Igor Pashkov, Mikhail Kisselyov, and Leonid A. Noskin "Laser correlation spectrometry: a new approach to organizing oncological screening for a population exposed to chronic irradiation", Proc. SPIE 4059, Laser Use in Oncology II, (30 December 1999); https://doi.org/10.1117/12.375274

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available