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The new biosensor of vitamin D synthetic capacity of solar/artificial UV-B radiation is based on liquid crystal with provitamin D dopant. Nematic liquid crystals (LC-805, ZLI-1695) are converted into induced cholesteric phase using photosensitive steroid biomolecules of provitamin D3 (7- dehydrocholesterol). During UV exposure remarkable decrease in the number of the Cano-Grandjean stripes has been observed in the wedge-like cell as a result of UV initiated photoisomerization of provitamin D3 that changed helical twisting power of the dopant molecules.
Irina P. Terenetskaya andI. A. Gvozdovskyy
"In-situ monitoring of biologically active solar UV-B radiation: a new biosensor of vitamin D synthetic capacity", Proc. SPIE 4425, Selected Papers from the International Conference on Optoelectronic Information Technologies, (12 June 2001); https://doi.org/10.1117/12.429721
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Irina P. Terenetskaya, I. A. Gvozdovskyy, "In-situ monitoring of biologically active solar UV-B radiation: a new biosensor of vitamin D synthetic capacity," Proc. SPIE 4425, Selected Papers from the International Conference on Optoelectronic Information Technologies, (12 June 2001); https://doi.org/10.1117/12.429721