Raman spectroscopy of biological material: results from the RAAD common sample set phase II

Kristina R. Gonser; Steven D. Christesen; Jason A. Guicheteau

doi:10.1117/12.577591

16 December 2004 Raman spectroscopy of biological material: results from the RAAD common sample set phase II

Kristina R. Gonser, Steven D. Christesen, Jason A. Guicheteau

Proceedings Volume 5585, Chemical and Biological Point Sensors for Homeland Defense II; (2004) https://doi.org/10.1117/12.577591
Event: Optics East, 2004, Philadelphia, Pennsylvania, United States

Abstract

Raman spectroscopy is just one of the diverse set of detection techniques which, under the CB Rapid Agent Aerosol Detection (RAAD) program, are being evaluated for their ability to detect and identify biological materials. In order to compare and contrast different techniques, a Common Sample Set composed of threat simulants, interferents and growth media was provided to all RAAD participants. The samples were investigated using both normal Raman and surface-enhanced Raman spectroscopy. This paper focuses on near-infrared Raman data from the Common Sample Set bacterial simulants. Results are also given from a principal component analysis performed on these samples. These measurements provide and initial assessment of the detection and discrimination capability of Raman spectroscopy as applied to biological materials. Despite the challenges facing this detection method, Raman spectroscopy is emerging as a rapid and information-rich method of investigating biological threats.

Citation Download Citation

Kristina R. Gonser, Steven D. Christesen, and Jason A. Guicheteau "Raman spectroscopy of biological material: results from the RAAD common sample set phase II", Proc. SPIE 5585, Chemical and Biological Point Sensors for Homeland Defense II, (16 December 2004); https://doi.org/10.1117/12.577591

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available