MRI and SPECT fusion for epilepsy lateralization

Kourosh Jafari-Khouzani; Hamid Soltanian-Zadeh; Kost Elisevich

doi:10.1117/12.596401

14 April 2005 MRI and SPECT fusion for epilepsy lateralization

Kourosh Jafari-Khouzani, Hamid Soltanian-Zadeh, Kost Elisevich

Proceedings Volume 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images; (2005) https://doi.org/10.1117/12.596401
Event: Medical Imaging, 2005, San Diego, California, United States

Abstract

This paper presents a study on the SPECT images of the brain with the aim of determining the hippocampus abnormality and consequently applying timely treatment. Intensity and volume features of the hippocampus from brain MRI have been shown to be useful in detecting the abnormal hippocampus in TLE. In this study, we evaluate the intensity information of the SPECT images of the brain for the purpose of early detection of abnormal hippocampus, before the brain tissue is damaged and MRI features change. The hippocampi are segmented manually by an expert from T1-weighted MR images. The segmented regions are mapped on the corresponding SPECT images using the mutual information technique. The mean and standard deviation of the hippocampi from SPECT images are used to determine abnormal hippocampus. The experimental results show that SPECT images analyzed along with MRI generate quantitative information useful for the treatment and evaluation of epileptic patients.

Citation Download Citation

Kourosh Jafari-Khouzani, Hamid Soltanian-Zadeh, and Kost Elisevich "MRI and SPECT fusion for epilepsy lateralization", Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); https://doi.org/10.1117/12.596401

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