In vitro retinal imaging with full field swept source optical coherence tomography

James Fergusson; Boris Považay; Bernd Hofer; Wolfgang Drexler

doi:10.1117/12.843254

19 February 2010 In vitro retinal imaging with full field swept source optical coherence tomography

James Fergusson, Boris Považay, Bernd Hofer, Wolfgang Drexler

Proceedings Volume 7554, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV; 75540I (2010) https://doi.org/10.1117/12.843254
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Weakly scattering tree shrew retina has been imaged in vitro with full field swept source optical coherence tomography, visualising multiple intraretinal layers. The system utilises a 50nm bandwidth Superlum SLD, to acheive ~8μm of axial resolution and 4μm of transversal resolution. Volumetric images of retinal tissue with dimensions of 1248x936x678μm (horizontal by vertical by axial) were recorded in two second (equivalent of 153,600 A-scans per second) with a measured signal to noise ratio of 75dB. From the 5mW of SLD optical power available, 720μW illuminates the sample, giving a power per pixel of 4.6nW, ten times less power per pixel then standard FDOCT systems. After upgrading the camera and redesigning the optical beam path, 82dB of SNR was realised.

Citation Download Citation

James Fergusson, Boris Považay, Bernd Hofer, and Wolfgang Drexler "In vitro retinal imaging with full field swept source optical coherence tomography", Proc. SPIE 7554, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, 75540I (19 February 2010); https://doi.org/10.1117/12.843254

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