Extracting quantitative biomechanical parameters for cartilage from second harmonic generation images

Magnus B. Lilledahl; David M. Pierce; Tim Ricken; Gerhard A. Holzapfel; Catarina de Lange Davies

doi:10.1117/12.888087

22 February 2011 Extracting quantitative biomechanical parameters for cartilage from second harmonic generation images

Magnus B. Lilledahl, David M. Pierce, Tim Ricken, Gerhard A. Holzapfel, Catarina de Lange Davies

Author Affiliations +

Proceedings Volume 7903, Multiphoton Microscopy in the Biomedical Sciences XI; 79033A (2011) https://doi.org/10.1117/12.888087
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

Cartilage from the medial femoral condyle of chicken was sectioned and imaged using second harmonic generation microscopy. Using image analysis techniques based on the Fourier transform we derived quantitative threedimensional data of the fiber direction and dispersion of the collagen fiber network in the superficial layer. These data can be used directly in biomechanical models to enhance the fidelity of these models.

Citation Download Citation

Magnus B. Lilledahl, David M. Pierce, Tim Ricken, Gerhard A. Holzapfel, and Catarina de Lange Davies "Extracting quantitative biomechanical parameters for cartilage from second harmonic generation images", Proc. SPIE 7903, Multiphoton Microscopy in the Biomedical Sciences XI, 79033A (22 February 2011); https://doi.org/10.1117/12.888087

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