Colloidal ZnO nanoparticles for nonlinear optical probes and selective cell destruction

Ben E. Urban; Purnima Neogi; Yasuhisa Fujita; Arup Neogi

doi:10.1117/12.2005938

22 February 2013 Colloidal ZnO nanoparticles for nonlinear optical probes and selective cell destruction

Ben E. Urban, Purnima Neogi, Yasuhisa Fujita, Arup Neogi

Author Affiliations +

Proceedings Volume 8595, Colloidal Nanocrystals for Biomedical Applications VIII; 85950M (2013) https://doi.org/10.1117/12.2005938
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

ZnO nanoparticles are notoriously difficult to use as optical probes due to the energy required for excitation. Nonlinear properties give a way around the high energy necessary for excitation. By using second harmonic generation, SHG, and multiphoton excitation, MPE, it is possible to use NIR light to generate intense coherent light that does not lead to heating of the cell or noncoherent light that also leads to sudden heating of the cell and cell destruction.

Citation Download Citation

Ben E. Urban, Purnima Neogi, Yasuhisa Fujita, and Arup Neogi "Colloidal ZnO nanoparticles for nonlinear optical probes and selective cell destruction", Proc. SPIE 8595, Colloidal Nanocrystals for Biomedical Applications VIII, 85950M (22 February 2013); https://doi.org/10.1117/12.2005938

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