Autofluorescent polarimetry of bile films in the liver pathology differentiation

V. P. Prysyazhnyuk; Yu. O. Ushenko; O. V. Dubolazov; A. G. Ushenko; V. O. Savich; A. O. Karachevtsev

doi:10.1117/12.2187446

22 September 2015 Autofluorescent polarimetry of bile films in the liver pathology differentiation

V. P. Prysyazhnyuk, Yu. O. Ushenko, O. V. Dubolazov, A. G. Ushenko, V. O. Savich, A. O. Karachevtsev

Proceedings Volume 9599, Applications of Digital Image Processing XXXVIII; 959921 (2015) https://doi.org/10.1117/12.2187446
Event: SPIE Optical Engineering + Applications, 2015, San Diego, California, United States

Abstract

A new information optical technique of diagnostics of the structure of the polycrystalline bile films is proposed. The model of Mueller-matrix description of mechanisms of optical anisotropy of such objects as optical activity, birefringence, as well as linear and circular dichroism is suggested. The ensemble of informationally topical azimuthally stable Mueller-matrix invariants is determined. Within the statistical analysis of such parameters distributions the objective criteria of differentiation of the polycrystalline bile films taken from patients with fatty degeneration (group 1) chronic hepatitis (group 2) of the liver were determined. From the point of view of probative medicine the operational characteristics (sensitivity, specificity and accuracy) of the information-optical method of Mueller-matrix mapping of polycrystalline films of bile were found and its efficiency in diagnostics of pathological changes was demonstrated.

Citation Download Citation

V. P. Prysyazhnyuk, Yu. O. Ushenko, O. V. Dubolazov, A. G. Ushenko, V. O. Savich, and A. O. Karachevtsev "Autofluorescent polarimetry of bile films in the liver pathology differentiation", Proc. SPIE 9599, Applications of Digital Image Processing XXXVIII, 959921 (22 September 2015); https://doi.org/10.1117/12.2187446

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