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The CID Number appears on each page of the manuscript. The complete citation is used on the first page, and an abbreviated version on subsequent pages. AuthorsNumbers in the index correspond to the last two digits of the six-digit citation identifier (CID) article numbering system used in Proceedings of SPIE. The first four digits reflect the volume number. Base 36 numbering is employed for the last two digits and indicates the order of articles within the volume. Numbers start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B...0Z, followed by 10-1Z, 20-2Z, etc. Adashov, Arkady, 0I Ahmad, Mahmoud, 0Y Ak, Ayşe, 0Q Anand, Sanjay, 0E, 0K Andreozzi, Jacqueline, 0X, 10 Arce-Diego, J. L., 0Z Arnason, Stephen, 0C Bagnato, Vanderlei Salvador, 13, 14, 15, 17 Bandera, Yuriy, 0P Baran, Timothy M., 18 Blanco, Kate Cristina, 14 Bruce, Terri F., 0P Buller, Gerald, 06 Burdette, Mary K., 0P Carvalho, Mariana Torres, 15 Cass, Anthony, 0G Celli, Jonathan P., 0C, 0J Chen, Bin, 07 Corrêa, Thaila Quatrini, 13, 14, 15 Cramer, Gwendolyn, 0J Cuckov, Filip, 0C Daly, Liam, 0C Darafsheh, Arash, 0Y de Souza, Clovis Wesley Oliveira, 15 El-Hamidi, Hamid, 0J Elson, Daniel S., 0G Fanjul-Vélez, F., 0Z Finlay, Jarod C., 0D, 0L, 0Y Foster, Thomas H., 18 Foulger, Stephen H., 0P Gallina, Maria Elena, 0G Gemmell, Nathan R., 06 Geralde, Mariana Carreira, 15 Gladstone, David, 0X Glaser, Adam K., 0X Grecco, Clóvis, 17 Gülsoy, Murat, 0Q Gunn, Jason, 08, 10 Hadfield, Robert H., 06 Hanna, George, 0G Hasan, Tayyaba, 0C, 0K Hempstead, Joshua, 0C Inada, Natalia Mayumi, 13, 14 Jafari, Seyedehrojin, 0J Jones, Dustin P., 0J Kahraman, Mehmet, 12 Kanick, Stephen Chad, 10 Kessel, David, 02 Khan, Amjad Pervez, 0C Kim, Michele M., 06, 0D, 0L, 0T, 0Y Korkmaz, Aysun, 12 Kraus, Daniel, 07 Kurachi, Cristina, 10, 13, 14, 15, 17 Liu, Hui, 0C Liu, Yiran, 0C Ma, Daqing, 0G Mallidi, Srivalleesha, 0C Marangoni, Valéria S., 13 Marra, Kayla, 08, 10 Maytin, Edward V., 0E, 0K McCarthy, Aongus, 06 Nabavi, Elham, 0G Nieskoski, Michael D., 08 Nogueira, Marcelo Saito, 10 Penjweini, Rozhin, 06, 0D, 0L, 0T Pogue, Brian W., 08, 0X, 10 Powell, Rhonda R., 0P Pratavieira, Sebastião, 14, 17 Qiu, Haixia, 0T Rizvi, Imran, 0C Rudd, Grant, 0C Rudnitsky, Arkady, 0I Ruhi, Mustafa Kemal, 0Q Salas-García, I., 0Z Samkoe, Kimberley S., 10 Sheinman, Victor, 0I Singh, Mohan, 0G Suzuki, Isabella L., 13 Teles de Andrade, Cintia, 10 Thomas, Erik, 0K Thomas, Richard, 0C Toktosunov, Aitmamat, 0I Trembly, B. Stuart, 08 Tzoy, Andrey, 0I Veilleux, Israel, 06 Wilson, Brian C., 06 Yilmaz, Yusuf, 12 Zalevsky, Zeev, 0I Zhang, Rongxiao, 0X Zhao, Hailin, 0G Zhou, Yu, 0G Zhu, Timothy C., 06, 0D, 0L, 0T, 0Y Zucolotto, Valtencir, 13 Conference CommitteeSymposium Chairs James G. Fujimoto, Massachusetts Institute of Technology (United States) R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts General Hospital (United States) and Harvard School of Medicine (United States)
Program Track Chair Conference Chairs David H. Kessel, Wayne State University (United States) Tayyaba Hasan, Massachusetts General Hospital (United States)
Conference Program Committee Imran Rizvi, Brigham and Women’s Hospital (United States) Jonathan P. Celli, University of Massachusetts Boston (United States)
Session Chairs 1 Photodynamic Therapy I David H. Kessel, Wayne State University School of Medicine (United States) 2 Photodynamic Therapy II Tayyaba Hasan, Wellman Center for Photomedicine (United States) 3 Photodynamic Therapy III Jonathan P. Celli, University of Massachusetts Boston (United States) 4 Photodynamic Therapy IV Theresa M. Busch, University of Pennsylvania (United States) 5 Photodynamic Therapy V Timothy C. Zhu, The University of Pennsylvania Health System (United States) 6 Photodynamic Therapy VI Kimberley S. Samkoe, Geisel School of Medicine (United States) 7 Photodynamic Therapy VII Scott C. Davis, Thayer School of Engineering at Dartmouth (United States) 8 Photodynamic Therapy VIII Imran Rizvi, Brigham and Women’s Hospital (United States)
IntroductionSPIE has been sponsoring conferences related to topics in photodynamic therapy since 1987. The first symposium was organized by Douglas Neckers, with Michael Detty, Tayyaba Hasan and Angelo Russo as co-chairs. Thomas Dougherty then organized a continuing series of these symposia beginning in 1989 with the assistance of Dr. Hasan. A special symposium on ‘New Directions’ was organized by Charles J. Gomer in 1990. Since 2003, the annual PDT conferences were organized by David Kessel, with Tayyaba Hasan becoming co-chair in 2011. These meetings are designed to bring together workers involved in synthesis, characterization and development of photodynamic processes. A diverse group of people participate including chemists, biologists, clinical personnel, and engineers. Research was initially directed at assessing the role of PDT in the treatment of cancer. More recently, effects on microbial infections and other indications have been explored. A series of newer agents for better cancer control are being developed, along with light sources and dosimetry decides to simplify the calculations involved and light delivery procedures. The role of immunologic processes are also being evaluated. The impact of PDT on cancer control has been demonstrated, but major clinical utilization appears to be in Asia and Europe. Part of the slow acceptance in the US may be related to regulatory requirements along with decisions by pharmaceutical groups to aim their resources in other directions. Examples of successful treatment of pathologic conditions by PDT continue to be reported. As evidence continues to accrue, perhaps the efficacy of this form of therapy will eventually prove persuasive. David H. Kessel Tayyaba Hasan
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