Particle streak velocimetry-OCT (PSV-OCT): a novel method for multi-vector component velocimetry of microscale flow physiology
(Conference Presentation)

Kevin C. Zhou; Brendan K. Huang; Ute A. Gamm; Vineet Bhandari M.D.; Mustafa K. Khokha; Michael A. Choma M.D.

doi:10.1117/12.2214794

26 April 2016 Particle streak velocimetry-OCT (PSV-OCT): a novel method for multi-vector component velocimetry of microscale flow physiology (Conference Presentation)

Kevin C. Zhou, Brendan K. Huang, Ute A. Gamm, Vineet Bhandari M.D., Mustafa K. Khokha, Michael A. Choma M.D.

Author Affiliations +

Proceedings Volume 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX; 96970F (2016) https://doi.org/10.1117/12.2214794
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

We present a new method for 2.5 and 3 vector component velocimetry. We call this method particle streak velocimetry OCT (PSV-OCT). PSV-OCT generates two-dimensional, 2.5 vector component (v_x,|v_y|,v_z) cross-sectional maps of microscale flow velocity (e.g. biological cilia-driven fluid flow). The enabling insight is that a tracer particle in sparsely-seeded fluid flow traces out streaks in (x,z,t)-space. The streak orientations in x-t and z-t yield v_x and v_z, respectively. The in-plane (x-z plane) residence time yields the out-of-plane speed |v_y|. Vector component values are generated by fitting streaks to a model of image formation. We demonstrate cross-sectional estimation of (v_x,|v_y|,v_z) in two important animal models in ciliary biology: Xenopus embryos (tadpoles) and mouse trachea. Further, by incorporation the assumption of incompressible flow into the estimation process, we are able to generate 3 vector component (v_x,v_y,v_z) estimates in three spatial dimensions from 2.5 vector component measurements taken in parallel OCT planes in 3D space.

Conference Presentation

Citation Download Citation

Kevin C. Zhou, Brendan K. Huang, Ute A. Gamm, Vineet Bhandari M.D., Mustafa K. Khokha, and Michael A. Choma M.D. "Particle streak velocimetry-OCT (PSV-OCT): a novel method for multi-vector component velocimetry of microscale flow physiology (Conference Presentation)", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 96970F (26 April 2016); https://doi.org/10.1117/12.2214794

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Particles

Velocimetry

Optical coherence tomography

Animal model studies

Microfluidics

Physiology

3D modeling

Show All Keywords

Keywords/Phrases

Search In:

Publication Years