Second-harmonic radiating imaging probes and harmonic holography

Ye Pu; Demetri Psaltis

doi:10.1117/12.2238511

3 October 2016 Second-harmonic radiating imaging probes and harmonic holography

Ye Pu, Demetri Psaltis

Proceedings Volume 9956, Ultrafast Nonlinear Imaging and Spectroscopy IV; 995608 (2016) https://doi.org/10.1117/12.2238511
Event: SPIE Optical Engineering + Applications, 2016, San Diego, California, United States

Abstract

Compared with other imaging probes such as fluorescent dyes and quantum dots, second-harmonic radiating imaging probes (SHRIMPs) provide a unique ultrafast, coherent optical contrast that is free of photobleaching and emission intermittency. Using the second-harmonic signal emitted from SHRIMPs, harmonic holography achieves threedimensional holographic imaging with a color contrast similar to fluorescence microscopy where the uninterested background scattering is efficiently suppressed by an optical filter. The coherent contrast provided by SHRIMPs also enables imaging through turbid media via digital phase conjugation. Here we review the developments and applications of SHRIMPs and harmonic holography.

Conference Presentation

Citation Download Citation

Ye Pu and Demetri Psaltis "Second-harmonic radiating imaging probes and harmonic holography", Proc. SPIE 9956, Ultrafast Nonlinear Imaging and Spectroscopy IV, 995608 (3 October 2016); https://doi.org/10.1117/12.2238511

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