Subpixel motion correction for phase-sensitive optical coherence tomography

Huakun Li; Bingyao Tan; Vimal P. Pandiyan; Veluchamy A. Barathi; Ramkumar Sabesan; Leopold Schmetterer; Tong Ling

doi:10.1117/12.2650991

9 March 2023 Subpixel motion correction for phase-sensitive optical coherence tomography

Huakun Li, Bingyao Tan, Vimal P. Pandiyan, Veluchamy A. Barathi, Ramkumar Sabesan, Leopold Schmetterer, Tong Ling

Author Affiliations +

Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC123670U (2023) https://doi.org/10.1117/12.2650991
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Phase-sensitive optical coherence tomography (OCT) enables label-free imaging of structural dynamics with nanoscopic sensitivity. However, the inevitable bulk tissue motions degrade the signal stability and introduce extra phase error. To suppress the motion-induced phase error, we propose a phase-restoring subpixel motion correction method for post-hoc motion correction in Fourier domain OCT, which enables translational shifts of complex-valued OCT images by arbitrary distance. Phantom and in-vivo rodent optoretinogram imaging experiments were conducted to demonstrate the advantages of the proposed method over conventional pixel-level method and the Fourier transform based method.

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Citation Download Citation

Huakun Li, Bingyao Tan, Vimal P. Pandiyan, Veluchamy A. Barathi, Ramkumar Sabesan, Leopold Schmetterer, and Tong Ling "Subpixel motion correction for phase-sensitive optical coherence tomography", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC123670U (9 March 2023); https://doi.org/10.1117/12.2650991

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KEYWORDS

Optical coherence tomography

Optical calibration

Fourier transforms

In vivo imaging

Motion detection

Motion measurement

Signal detection

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