Grant Swajian,1 Junsoo Lee,2 Nitesh Katta,3 Bahman Anvari,1 Thomas E. Milner3
1Univ. of California, Riverside (United States) 2Univ. of California, Irvine (United States) 3Beckman Laser Institute and Medical Clinic (United States)
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A major constraint in photomedicine is the scattering of photons within tissue, which can limit the penetration of light to reach target structures such as a tumor. Laser-induced shockwaves could offer a potential approach to mitigate this constraint by modifying the optical scattering properties of tissue and re-directing the light to targeted regions. Preliminary results in a skin phantom suggest that laser-induced shockwaves can alter optical characteristics of a turbid medium, and subsequently, induce changes in light propagation.
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Grant Swajian, Junsoo Lee, Nitesh Katta, Bahman Anvari, Thomas E. Milner, "Effects of laser-induced shockwaves on light propagation in turbid media," Proc. SPIE PC12377, Optical Interactions with Tissue and Cells XXXIV, PC1237702 (7 March 2023); https://doi.org/10.1117/12.2648002