Quantum dots (QDs) are nanocrystals composed of semiconductors that have been used as probes, sensors, and labels in life sciences research for more than 25 years. Broad adoption of QDs has been impeded by nuances of their colloidal nature, often leading to unreliable measurements in the hands of end users. Coatings contribute to QD colloidal properties and major efforts have aimed to engineer hydrophilic adsorbates that stabilize QDs in aqueous solution while preventing nonspecific binding and steric hindrance that limit applications. This talk will describe the historical development of QD coatings, current challenges, and recent advancements in the field.
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