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13 March 2024 A disposable through-needle fiber-optic sensor for in-vivo assessment of deep-tissue biomechanical properties
Shuo Yang, Jingwei Ling, Ziang Feng, Song Hu
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Proceedings Volume PC12835, Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV; PC1283508 (2024) https://doi.org/10.1117/12.3002690
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
We report a fiber-optic sensor that can be deployed through a standard 250-µm injection needle (25 gauge) for minimally invasive measurements of deep-tissue biomechanical properties in vivo. We have demonstrated the sensor’s ability to provide distinct readouts of muscle stiffness when the hind limb of a rat is relaxed and stretched. To ensure minimal tissue damage and distortion, we have integrated optical proximity sensing within the same fiber for real-time, precise control of the sensor position. To facilitate clinical translation, we have designed the sensor to be disposable and autoclavable and have developed a strategy for mass production.
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Shuo Yang, Jingwei Ling, Ziang Feng, and Song Hu "A disposable through-needle fiber-optic sensor for in-vivo assessment of deep-tissue biomechanical properties", Proc. SPIE PC12835, Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV, PC1283508 (13 March 2024); https://doi.org/10.1117/12.3002690
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KEYWORDS
Biomechanics
Tissues
Fiber optics sensors
In vivo imaging
Sensors
Muscles
Optical sensing
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