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1 May 2010 Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm
Rami Nachabe, Benno H. W. Hendriks, Adrien E. Desjardins, Marjolein van der Voort, Martin B. van der Mark, Henricus J. C. M. Sterenborg
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Journal of Biomedical Optics, Vol. 15, Issue 3, 037015 (May 2010). https://doi.org/10.1117/1.3454392
Abstract
We demonstrate a method to estimate the concentrations of water and lipid in scattering media such as biological tissues with diffuse optical spectra acquired over the range of 900 to 1600 nm. Estimations were performed by fitting the spectra to a model of light propagation in scattering media derived from diffusion theory. To validate the method, spectra were acquired from tissue phantoms consisting of lipid and water emulsions and swine tissues ex vivo with a two-fiber probe.
©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Rami Nachabe, Benno H. W. Hendriks, Adrien E. Desjardins, Marjolein van der Voort, Martin B. van der Mark, and Henricus J. C. M. Sterenborg "Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm," Journal of Biomedical Optics 15(3), 037015 (1 May 2010). https://doi.org/10.1117/1.3454392
Published: 1 May 2010
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Cited by 123 scholarly publications and 71 patents.
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KEYWORDS
Absorption
Tissues
Scattering
Optical fibers
Biological research
Scattering media
Water
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