Open Access
1 September 2005 Toward the clinical application of time-domain fluorescence lifetime imaging
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Abstract
High-speed (video-rate) fluorescence lifetime imaging (FLIM) through a flexible endoscope is reported based on gated optical image intensifier technology. The optimization and potential application of FLIM to tissue autofluorescence for clinical applications are discussed.
©(2005) Society of Photo-Optical Instrumentation Engineers (SPIE)
Ian H. Munro, James A. McGinty, Neil P. Galletly, Jose Requejo-Isidro, Peter M. P. Lanigan, Daniel S. Elson, Christopher W. Dunsby, Mark A.A. Neil, M. John Lever, Gordon W. H. Stamp, and Paul M.W. French "Toward the clinical application of time-domain fluorescence lifetime imaging," Journal of Biomedical Optics 10(5), 051403 (1 September 2005). https://doi.org/10.1117/1.2102807
Published: 1 September 2005
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CITATIONS
Cited by 75 scholarly publications and 2 patents.
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KEYWORDS
Fluorescence lifetime imaging

Luminescence

Tissues

Endoscopes

Tissue optics

Endoscopy

Signal to noise ratio

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