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1 July 2006 Collagen solubility correlates with skin optical clearing
Jason Hirshburg, Bernard Choi, J. Stuart Nelson M.D., Alvin T. Yeh
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Journal of Biomedical Optics, Vol. 11, Issue 4, 040501 (July 2006). https://doi.org/10.1117/1.2220527
Abstract
Biomedical optics and photomedicine applications are challenged by the turbidity of most biological tissue systems. Nonreactive, biocompatible chemical agents can induce a reversible reduction in optical scattering of collagenous tissues such as human skin. Herein we show that a chemical agent's tissue optical clearing potential is directly related to its collagen solubility, providing a rational design basis for effective, percutaneous formulations.
©(2006) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Jason Hirshburg, Bernard Choi, J. Stuart Nelson M.D., and Alvin T. Yeh "Collagen solubility correlates with skin optical clearing," Journal of Biomedical Optics 11(4), 040501 (1 July 2006). https://doi.org/10.1117/1.2220527
Published: 1 July 2006
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Cited by 91 scholarly publications and 2 patents.
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KEYWORDS
Collagen
Skin
Tissue optics
Optical clearing
Chemical analysis
Refractive index
Scattering
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