Temperature-dependent optical properties of Intralipid® measured with frequency-domain photon-migration spectroscopy

Biju Cletus; Rainer Kunnemeyer; Paul Martinsen; V. Andrew McGlone

doi:10.1117/1.3290820

1 January 2010 Temperature-dependent optical properties of Intralipid® measured with frequency-domain photon-migration spectroscopy

Biju Cletus, Rainer Kunnemeyer, Paul Martinsen, V. Andrew McGlone

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Journal of Biomedical Optics, Vol. 15, Issue 1, 017003 (January 2010). https://doi.org/10.1117/1.3290820

Abstract

We present the temperature dependence of absorption and reduced scattering coefficients of 1.8% Intralipid measured by frequency-domain photon-migration spectroscopy between 710 and 850 nm. These measurements were made in the physiologically relevant 30 to 40°C temperature range. The temperature coefficients for absorption were consistent during heating and cooling and follow closely other reported results. The change in absorption coefficient at 740 nm suggests that a minimum temperature change of 4°C is observable within the error limits. We found that the reduced scattering coefficient shows a hysteresis with temperature at 740 nm. The temperature coefficient for reduced scattering determined from heating cycle measurements agrees with theory and other measurements within the error limits.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Biju Cletus, Rainer Kunnemeyer, Paul Martinsen, and V. Andrew McGlone "Temperature-dependent optical properties of Intralipid® measured with frequency-domain photon-migration spectroscopy," Journal of Biomedical Optics 15(1), 017003 (1 January 2010). https://doi.org/10.1117/1.3290820

Published: 1 January 2010

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