Open Access
14 March 2013 Acoustic attenuation compensation in photoacoustic tomography using time-variant filtering
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Abstract
Most reconstruction algorithms used in photoacoustic tomography do not account for the effects of acoustic attenuation on the recorded signals. For experimental measurements made in biological tissue, the frequency dependent acoustic attenuation causes high frequency components of the propagating photoacoustic waves to be significantly reduced. This signal loss manifests as a depth dependent magnitude error and blurring of features within the reconstructed image. Here, a general method for compensating for this attenuation using time-variant filtering is presented. The time-variant filter is constructed to correct for acoustic attenuation and dispersion following a frequency power law under the assumption the distribution of attenuation parameters is homogeneous. The filter is then applied directly to the recorded time-domain signals using a form of nonstationary convolution. Regularization is achieved using a time-variant window where the cutoff frequency is based on the local time-frequency distribution of the recorded signals. The approach is computationally efficient and can be used in combination with any detector geometry or reconstruction algorithm. Numerical and experimental examples are presented to illustrate the utility of the technique. Clear improvements in the magnitude and resolution of reconstructed photoacoustic images are seen when acoustic attenuation compensation is applied.
© 2013 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2013/$25.00 © 2013 SPIE
Bradley E. Treeby "Acoustic attenuation compensation in photoacoustic tomography using time-variant filtering," Journal of Biomedical Optics 18(3), 036008 (14 March 2013). https://doi.org/10.1117/1.JBO.18.3.036008
Published: 14 March 2013
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CITATIONS
Cited by 74 scholarly publications.
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KEYWORDS
Signal attenuation

Acoustics

Electronic filtering

Photoacoustic spectroscopy

Photoacoustic tomography

Time-frequency analysis

Absorption

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