Fiber-optic raster scanning two-photon endomicroscope using a tubular piezoelectric actuator

Dukho Do; Hongki Yoo; Dae-Gab Gweon

doi:10.1117/1.JBO.19.6.066010

27 June 2014 Fiber-optic raster scanning two-photon endomicroscope using a tubular piezoelectric actuator

Dukho Do, Hongki Yoo, Dae-Gab Gweon

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Journal of Biomedical Optics, Vol. 19, Issue 6, 066010 (June 2014). https://doi.org/10.1117/1.JBO.19.6.066010

Abstract

A nonresonant, fiber-optic raster scanning endomicroscope was developed using a quarter-tubular piezoelectric (PZT) actuator. A fiber lever mechanism was utilized to enhance the small actuation range of the tubular PZT actuator and to increase its field-of-view. Finite element method simulation of the endoscopic probe was conducted for various conditions to maximize its scanning range. After fabricating the probe using a double clad fiber, we obtained two-photon fluorescence images using raster beam scanning of the fiber. The outer diameter of the probe was 3.5 mm and its rigid distal length was 30 mm including a high numerical aperture gradient index lens. These features are sufficient for input into the instrumental channel of a commercial colonoscope or gastroscope to obtain high resolution images in vivo.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Dukho Do, Hongki Yoo, and Dae-Gab Gweon "Fiber-optic raster scanning two-photon endomicroscope using a tubular piezoelectric actuator," Journal of Biomedical Optics 19(6), 066010 (27 June 2014). https://doi.org/10.1117/1.JBO.19.6.066010

Published: 27 June 2014

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