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2 January 2018 Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry
Irina Y. Yanina, Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, Valery V. Tuchin
Author Affiliations +
Funded by: Academy of Finland, Suomen Akatemia (Academy of Finland), Russian Presidential, Russian Presidential for Support of Young Researchers, President of the Russian Federation, State Support of Leading Schools, Ministry of Education and Science of the Russian Federation, Government of Russian Federation, Government of the Russian Federation, Russian Government, University of Oulu and Government of Russian Federation, RF Government, Tomsk State University Competitiveness Improvement Programme, Russian Science Foundation
Journal of Biomedical Optics, Vol. 23, Issue 1, 016003 (January 2018). https://doi.org/10.1117/1.JBO.23.1.016003
Abstract
Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1- to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.
© 2018 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2018/$25.00 © 2018 SPIE
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Irina Y. Yanina, Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, and Valery V. Tuchin "Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry," Journal of Biomedical Optics 23(1), 016003 (2 January 2018). https://doi.org/10.1117/1.JBO.23.1.016003
Received: 16 August 2017; Accepted: 12 December 2017; Published: 2 January 2018
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KEYWORDS
Optical coherence tomography
Tissue optics
Temperature metrology
Refractometry
Tissues
Prisms
Biomedical optics
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