Weak light emission of soft tissues induced by heating

Antonello E. Spinelli; Giovanni Durando; Federico Boschi

doi:10.1117/1.JBO.23.4.046003

12 April 2018 Weak light emission of soft tissues induced by heating

Antonello E. Spinelli, Giovanni Durando, Federico Boschi

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Journal of Biomedical Optics, Vol. 23, Issue 4, 046003 (April 2018). https://doi.org/10.1117/1.JBO.23.4.046003

Abstract

The main goal of this work is to show that soft tissue interaction with high-intensity focused ultrasound (HIFU) or direct heating leads to a weak light emission detectable using a small animal optical imaging system. Our results show that the luminescence signal is detectable after 30 min of heating, resembling the time scale of delayed luminescence. The imaging of a soft tissue after heating it using an HIFU field shows that the luminescence pattern closely matches the shape of the cone typical of the HIFU beam. We conclude that heating a soft tissue using two different sources leads to the emission of a weak luminescence signal from the heated region with a decay half-life of a few minutes (4 to 6 min). The origin of such light emission needs to be further investigated.

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Antonello E. Spinelli, Giovanni Durando, and Federico Boschi "Weak light emission of soft tissues induced by heating," Journal of Biomedical Optics 23(4), 046003 (12 April 2018). https://doi.org/10.1117/1.JBO.23.4.046003

Received: 4 January 2018; Accepted: 19 March 2018; Published: 12 April 2018

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