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24 September 2018 Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications
Roshan Dsouza, Jungeun Won, Guillermo L. Monroy, Darold R. Spillman Jr., Stephen A. Boppart
Author Affiliations +
Funded by: US National Institutes of Health (NIH), National Institute for Biomedical Imaging and Bioengineering and the National Cancer Institute of the National Institutes of Health
Journal of Biomedical Optics, Vol. 23, Issue 9, 096003 (September 2018). https://doi.org/10.1117/1.JBO.23.9.096003
Abstract
Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT contains all associated optical hardware, including light source, spectrometer, hand-held probe, and a laptop. Additionally, this system utilizes unique real-time mosaicking of surface video images that are synchronized with rapid A-scan acquisition to eliminate the need for lateral scanning hardware, and enable the construction of cross-sectional B-mode images over extended lateral distances. The entire briefcase system weighs 9 kg and costs ∼USD$8000 using off-the-shelf components. System performance was validated by acquiring images of in vivo human skin on the fingertip, palm, and nail fold. The efficiency, portability, and low-cost enable accessibility and utility in primary care centers and low-resource settings.
© 2018 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2018/$25.00 © 2018 SPIE
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Roshan Dsouza, Jungeun Won, Guillermo L. Monroy, Darold R. Spillman Jr., and Stephen A. Boppart "Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications," Journal of Biomedical Optics 23(9), 096003 (24 September 2018). https://doi.org/10.1117/1.JBO.23.9.096003
Received: 14 March 2018; Accepted: 29 August 2018; Published: 24 September 2018
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Cited by 17 scholarly publications and 3 patents.
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KEYWORDS
Optical coherence tomography
Imaging systems
Spectroscopy
In vivo imaging
Point-of-care devices
Skin
Mirrors
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