Challenges and advances in two-dimensional photoacoustic computed tomography: a review

Shunyao Zhang; Jingyi Miao; Lei S. Li

doi:10.1117/1.JBO.29.7.070901

12 July 2024 Challenges and advances in two-dimensional photoacoustic computed tomography: a review

Shunyao Zhang, Jingyi Miao, Lei S. Li

Author Affiliations +

Journal of Biomedical Optics, Vol. 29, Issue 7, 070901 (July 2024). https://doi.org/10.1117/1.JBO.29.7.070901

Abstract

Significance

Photoacoustic computed tomography (PACT), a hybrid imaging modality combining optical excitation with acoustic detection, has rapidly emerged as a prominent biomedical imaging technique.

Aim

We review the challenges and advances of PACT, including (1) limited view, (2) anisotropy resolution, (3) spatial aliasing, (4) acoustic heterogeneity (speed of sound mismatch), and (5) fluence correction of spectral unmixing.

Approach

We performed a comprehensive literature review to summarize the key challenges in PACT toward practical applications and discuss various solutions.

Results

There is a wide range of contributions from both industry and academic spaces. Various approaches, including emerging deep learning methods, are proposed to improve the performance of PACT further.

Conclusions

We outline contemporary technologies aimed at tackling the challenges in PACT applications.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

Citation Download Citation

Shunyao Zhang, Jingyi Miao, and Lei S. Li "Challenges and advances in two-dimensional photoacoustic computed tomography: a review," Journal of Biomedical Optics 29(7), 070901 (12 July 2024). https://doi.org/10.1117/1.JBO.29.7.070901

Received: 18 October 2023; Accepted: 19 June 2024; Published: 12 July 2024

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