Rapid inverse radiative transfer solver for multiparameter spectrophotometry without integrating sphere

Jiahong Jin; Zachary D. Jones; Jun Q. Lu; Xin-Hua Hu

doi:10.1117/1.JBO.29.S1.S11508

2 January 2024 Rapid inverse radiative transfer solver for multiparameter spectrophotometry without integrating sphere

Jiahong Jin, Zachary D. Jones, Jun Q. Lu, Xin-Hua Hu

Author Affiliations +

Journal of Biomedical Optics, Vol. 29, Issue S1, S11508 (January 2024). https://doi.org/10.1117/1.JBO.29.S1.S11508

Abstract

Significance

Multiparameter spectrophotometry (MPS) provides a powerful tool for accurate characterization of turbid materials in applications such as analysis of material compositions, assay of biological tissues for clinical diagnosis and food safety monitoring.

Aim

This work is aimed at development and validation of a rapid inverse solver based on a particle swarm optimization (PSO) algorithm to retrieve the radiative transfer (RT) parameters of absorption coefficient, scattering coefficient and anisotropy factor of a turbid sample.

Approach

Monte Carlo (MC) simulations were performed to obtain calculated signals for comparison to the measured ones of diffuse reflectance, diffuse transmittance and forward transmittance. An objective function has been derived and combined with the PSO algorithm to iterate MC simulations for MPS.

Results

We have shown that the objective function can significantly reduce the variance in calculated signals by local averaging of an inverse squared error sum function between measured and calculated signals in RT parameter space. For validation of the new objective function for PSO based inverse solver, the RT parameters of 20% Intralipid solutions have been determined from 520 to 1000 nm which took about 2.7 minutes on average to complete signal measurement and inverse calculation per wavelength.

Conclusion

The rapid solver enables MPS to be translated into easy-to-use and cost-effective instruments without integrating sphere for material characterization by separating and revealing compositional profiles at the molecular and particulate scales.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

Citation Download Citation

Jiahong Jin, Zachary D. Jones, Jun Q. Lu, and Xin-Hua Hu "Rapid inverse radiative transfer solver for multiparameter spectrophotometry without integrating sphere," Journal of Biomedical Optics 29(S1), S11508 (2 January 2024). https://doi.org/10.1117/1.JBO.29.S1.S11508

Received: 24 August 2023; Accepted: 28 November 2023; Published: 2 January 2024

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KEYWORDS

Simulations

Particle swarm optimization

Photons

Spectrophotometry

Integrating spheres

Radiative transfer

Turbidity

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