Photoacoustic imaging of peripheral vessels in extremities by large-scale synthetic matrix array

Shuang Li; Guangjie Zhang; Yibing Wang; Wenzhao Li; Yu Sun; Changhui Li

doi:10.1117/1.JBO.29.S1.S11519

20 January 2024 Photoacoustic imaging of peripheral vessels in extremities by large-scale synthetic matrix array

Shuang Li, Guangjie Zhang, Yibing Wang, Wenzhao Li, Yu Sun, Changhui Li

Author Affiliations +

Journal of Biomedical Optics, Vol. 29, Issue S1, S11519 (January 2024). https://doi.org/10.1117/1.JBO.29.S1.S11519

Abstract

Significance

Various peripheral vascular diseases (PVD) in extremities, such as arterial atherosclerosis or venous occlusion in arm or legs, are a serious global health threat. Noninvasive vascular imaging is of great value for both diagnosis and assessment of PVD.

Approach

By scanning a one-dimensional non-focusing linear array, an equivalent large two-dimensional (2D) matrix array with hundreds of thousands or more ultrasound elements is formed, thereby achieving a wide signal reception angle as well as large imaging area for three-dimensional (3D) imaging of peripheral extremities.

Aim

To provide a feasible bedside and noninvasive imaging method for vascular imaging in extremities.

Results

Our system can achieve high-quality photoacoustic (PA) peripheral vessel imaging. The 3D subcutaneous vascular imaging results of the palms and arms of healthy volunteers demonstrate the superior performance of the system.

Conclusions

This work proposes a clinically oriented PA 3D subcutaneous vascular imaging system for human extremities. The system employs a synthetic matrix array via scanning a one-dimensional non-focusing linear probe, providing noninvasive, high-resolution, and high-contrast images of human extremities. It has potential application value in the diagnosis and monitoring of vascular diseases.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

Citation Download Citation

Shuang Li, Guangjie Zhang, Yibing Wang, Wenzhao Li, Yu Sun, and Changhui Li "Photoacoustic imaging of peripheral vessels in extremities by large-scale synthetic matrix array," Journal of Biomedical Optics 29(S1), S11519 (20 January 2024). https://doi.org/10.1117/1.JBO.29.S1.S11519

Received: 20 October 2023; Accepted: 2 January 2024; Published: 20 January 2024

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KEYWORDS

Imaging systems

Imaging arrays

Matrices

Photoacoustic imaging

3D image processing

Stereoscopy

Light sources and illumination

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