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1 October 2000 Optical coherence tomography of the rat cochlea
Brian Jet-Fei Wong M.D., Johannes F. de Boer, Boris Hyle Park, Zhongping Chen, J. Stuart Nelson M.D.
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Journal of Biomedical Optics, Vol. 5, Issue 4, (October 2000). https://doi.org/10.1117/1.1310165
Optical coherence tomography (OCT) was used to image the internal structure of a rat cochlea (ex vivo). Immediately following sacrifice, the temporal bone of a Sprague–Dawley rat was harvested. Axial OCT cross sectional images (over regions of interest, 1x1 mm– 2x8 mm) were obtained with a spatial resolution of 10–15 µm. The osseous borders of the lateral membranous labyrinth overlying the cochlea and the scala vestibuli, media, and tympani, which were well demarcated by the modiolus, Reissner’s and the basilar membranes, were clearly identified. OCT can be used to image internal structures in the cochlea without violating the osseous labyrinth using simple surgical exposure of the promontory, and may potentially be used to diagnose inner ear pathology in vivo in both animal and human subjects labyrinth.
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Brian Jet-Fei Wong M.D., Johannes F. de Boer, Boris Hyle Park, Zhongping Chen, and J. Stuart Nelson M.D. "Optical coherence tomography of the rat cochlea," Journal of Biomedical Optics 5(4), (1 October 2000). https://doi.org/10.1117/1.1310165
Published: 1 October 2000
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Cited by 42 scholarly publications and 62 patents.
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KEYWORDS
Optical coherence tomography
Bone
Ear
Mirrors
Pathology
Ultrasonography
Health sciences
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