Photon pathlength determination based on spatially resolved diffuse reflectance

Henrik Nilsson; Marcus Larsson; Gert E. Nilsson; Tomas Stroemberg

doi:10.1117/1.1482378

1 July 2002 Photon pathlength determination based on spatially resolved diffuse reflectance

Henrik Nilsson, Marcus Larsson, Gert E. Nilsson, Tomas Stroemberg

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Journal of Biomedical Optics, Vol. 7, Issue 3, (July 2002). https://doi.org/10.1117/1.1482378

A method for the prediction of the average photon pathlength in turbid media has been developed. The method is based on spatially resolved diffuse reflectance with discrete source detector distances up to 2 mm. Light reflectance was simulated using a Monte Carlo technique with a one-layer model utilizing a wide range of optical properties, relevant to human skin. At a source detector separation of 2 mm, the pathlength can vary sixfold due to differences in optical properties. By applying various preprocessing and prediction techniques, the pathlength can be predicted with a root-mean-square error of approximately 5%. Estimation of the photon pathlength can be used, e.g., to remove the influence of optical properties on laser Doppler flowmetry perfusion readings, which are almost linearly related to the average photon pathlength.

©(2002) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Henrik Nilsson, Marcus Larsson, Gert E. Nilsson, and Tomas Stroemberg "Photon pathlength determination based on spatially resolved diffuse reflectance," Journal of Biomedical Optics 7(3), (1 July 2002). https://doi.org/10.1117/1.1482378

Published: 1 July 2002

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