Plasmonic phototherapy using gold nanospheres and gold nanorods irradiated with light-emitting diodes

Gananathan Poorani; Aruna Prakasa Rao; Ganesan Singaravelu; Elanchezhiyan Manickan

doi:10.1117/1.JNP.10.026027

15 June 2016 Plasmonic phototherapy using gold nanospheres and gold nanorods irradiated with light-emitting diodes

Gananathan Poorani, Aruna Prakasa Rao, Ganesan Singaravelu, Elanchezhiyan Manickan

Author Affiliations +

Journal of Nanophotonics, Vol. 10, Issue 2, 026027 (June 2016). https://doi.org/10.1117/1.JNP.10.026027

Abstract

Gold nanoparticles (GNPs) provide different modes of therapeutic responses in cells depending on their size and shape. We have studied two modifications of GNPs exhibiting surface plasmon resonances (SPRs) with phototherapeutic effects in nonmalignant Vero and malignant HeLa cell lines. The cells were treated with 30-nm-size gold nanospheres (GNSs) (having SPR at a wavelength of 530 nm) and with gold nanorods (GNRs) (having SPR at 630 nm). The plasmonic phototherapy effect in cells was provided by irradiating them with green and red light-emitting diodes (LEDs). The cytotoxicities of GNPs were determined by MTT assay. Both the GNSs and GNRs were found to be biocompatible and have efficient phototherapeutic activity with LEDs.

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Gananathan Poorani, Aruna Prakasa Rao, Ganesan Singaravelu, and Elanchezhiyan Manickan "Plasmonic phototherapy using gold nanospheres and gold nanorods irradiated with light-emitting diodes," Journal of Nanophotonics 10(2), 026027 (15 June 2016). https://doi.org/10.1117/1.JNP.10.026027

Published: 15 June 2016

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