We discuss real-world challenges for multi-agent autonomy for defending high value targets using vision-based Unmanned Aerial Vehicles for detecting and intercepting adversarial intruders. Specifically, we address the defense of a hemispherical dome encapsulating high value targets. We discuss vision-based detection of intruders and the design of a control policy for pursuit and interception. We evaluate the performance of the algorithms in both the simulated environment and the real world. We extend the framework to multiple defenders and intruders using graph neural networks (GNNs). We show how GNNs can be trained on small graphs and deployed on large teams of defenders.
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