Dr. Alexander B. Vankov Profile

Dr. Alexander B. Vankov

Principal Scientist at J&J Vision

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Author

Publications (16)

SPIE Journal Paper | 11 September 2015 Open Access

Safety of cornea and iris in ocular surgery with 355-nm lasers

Jenny Wang, Jae Lim Chung, Georg Schuele, Alexander Vankov, Roopa Dalal, Michael Wiltberger, Daniel Palanker

JBO, Vol. 20, Issue 09, 095005, (September 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.9.095005

KEYWORDS: Cornea, Iris, Laser vision correction, Laser damage threshold, Safety, Laser safety, Iris recognition, Laser therapeutics, Eye, Surgery

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Proceedings Article | 5 March 2007 Paper

Progress toward a high-resolution retinal prosthesis

Alex Butterwick, Alex Vankov, Phil Huie, Karthik Vijayraghavan, Jim Loudin, Daniel Palanker

Proceedings Volume 6426, 64260R (2007) https://doi.org/10.1117/12.701787

KEYWORDS: Electrodes, Photodiodes, Visualization, Retina, Eye, LCDs, Neurons, Goggles, Information visualization, Video

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Proceedings Article | 7 March 2006 Paper

Dynamic range of safe electrical stimulation of the retina

Alexander Butterwick, Alexander Vankov, Phil Huie, Daniel Palanker

Proceedings Volume 6138, 61380Q (2006) https://doi.org/10.1117/12.650652

KEYWORDS: Electrodes, Laser damage threshold, Retina, Tissues, Glasses, Signal processing, Data modeling, Natural surfaces, In vitro testing, Experimental physics

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Proceedings Article | 7 March 2006 Paper

Plasma-mediated transfection of RPE

D. Palanker, T. Chalberg, A. Vankov, P. Huie, F. Molnar, A. Butterwick, M. Calos, M. Marmor, M. Blumenkranz

Proceedings Volume 6138, 61381E (2006) https://doi.org/10.1117/12.649624

KEYWORDS: Electrodes, Retina, Tissues, Content addressable memory, Eye, Ultrasonography, Luminescence, Eye models, In vivo imaging, Animal model studies

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Proceedings Article | 18 April 2005 Paper

Design of the optoelectronic high-resolution retinal prosthesis

Daniel Palanker, Alexander Vankov, Philip Huie, Mark Blumenkranz

Proceedings Volume 5688, (2005) https://doi.org/10.1117/12.590964

KEYWORDS: Electrodes, Retina, Image processing, Visualization, Eye, Photodiodes, Cameras, Goggles, LCDs, Infrared imaging

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Proceedings Article | 13 July 2004 Paper

Noninvasive monitoring of the thermal stress in RPE using light-scattering spectroscopy

Georg Schule, Philip Huie, Alexander Vankov, Edward Vitkin, Hui Fang, Eugene Hanlon, Lev Perelman, Daniel Palanker

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.529415

KEYWORDS: Light scattering, Scattering, Spectroscopy, Temperature metrology, Laser therapeutics, Refractive index, Photodynamic therapy, Optical testing, Lamps, Laser coagulation

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Proceedings Article | 13 July 2004 Paper

Electro-adhesive forceps for tissue manipulation

Alexander Vankov, Philip Huie, Mark Blumenkranz, Daniel Palanker

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.529723

KEYWORDS: Tissues, Electrodes, Metals, Natural surfaces, Cornea, Adhesives, Content addressable memory, Magnesium, Lead, Gold

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Proceedings Article | 13 July 2004 Paper

Attracting retinal cells to electrodes for high-resolution stimulation

Daniel Palanker, Philip Huie, Alexander Vankov, Yev Freyvert, Harvey Fishman, Michael Marmor, Mark Blumenkranz

Proceedings Volume 5314, (2004) https://doi.org/10.1117/12.529757

KEYWORDS: Electrodes, Retina, Visualization, Tissues, Surgery, In vitro testing, Platinum, Human-machine interfaces, Sodium, Natural surfaces

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Development of the electronic retinal prosthesis for restoration of sight in patients suffering from the degenerative retinal diseases faces many technological challenges. To achieve significant improvement in the low vision patients the visual acuity of 20/80 would be desirable, which corresponds to the pixel size of 20μm in the retinal implant. Stimulating current strongly (quadratically) depends on distance between electrode and cell. To achieve uniformity in stimulation thresholds, to avoid erosion of the electrodes and overheating of tissue, and to reduce the cross-talk between the neighboring pixels the neural cells should not be separated from electrodes by more than a few micrometers. Achieving such a close proximity along the whole surface of an implant is one of the major obstacles for the high resolution retinal implant. To ensure proximity of cells and electrodes we have developed a technique that prompts migration of retinal cells towards stimulating sites. The device consists of a multilayered membrane with an array of perforations of several (5-15) micrometers in diameter in which addressable electrodes can be embedded. In experiments in-vitro using explants of the whole retina of P7 rats, and in-vivo using adult rabbits and RCS rats the retinal tissue grew into the pores when membranes were positioned on the sub-retinal side. Histology has demonstrated that migrating cells preserve synaptic connections with cells outside the pores, thus allowing for signal transduction into the retina above the implant. Intimate proximity of cells to electrodes achieved with this technique allows for reduction of the stimulation current to 2μA at the 10μm electrode. A 3mm disk array with 18,000 pixels can stimulate cells with 0.5 ms pulses at 50Hz while maintaining temperature rise at the implant surface below 0.3°C. Such an implant can, in principle, provide spatial resolution geometrically corresponding to the visual acuity of 20/80 in a visual field of 10°.

Proceedings Article | 14 July 2003 Paper

Optimization of the pulsed electron avalanche knife for anterior segment surgery

Daniel Palanker, Alexander Vankov, Kalayaan Bilbao, Michael Marmor, Mark Blumenkranz

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.477954

KEYWORDS: Electrodes, Tissues, Surgery, Promethium, Liquids, Cavitation, Picosecond phenomena, Laser tissue interaction, Laser therapeutics, Plasma

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Proceedings Article | 27 June 2002 Paper

Effect of the probe geometry on dynamics of cavitation

Daniel Palanker, Alexander Vankov, Jason Miller

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472514

KEYWORDS: Tissues, Cavitation, Photography, Safety, Explosives, Laser tissue interaction, Surgery, Light emitting diodes, Luminescence, Particles

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Proceedings Article | 12 March 2001 Paper

High-precision long-distance remote sensing using chirped-pulse interferometry

Alexander Vankov, Vladimir Yashin

Proceedings Volume 4352, (2001) https://doi.org/10.1117/12.418783

KEYWORDS: Distance measurement, Interferometry, Amplifiers, Remote sensing, Streak cameras, LIDAR, Modulation, Picosecond phenomena, Optical amplifiers, Signal to noise ratio

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Proceedings Article | 8 December 1997 Paper

Compression of high-energy laser pulses after self-phase modulation in a bulk nonlinear medium

Vladimir Yashin, Alexander Vankov, Aleksey Kozlov, Sergey Chizhov, Alexander Andreev, Alexander Sutyagin

Proceedings Volume 3047, (1997) https://doi.org/10.1117/12.294290

KEYWORDS: Spatial filters, Modulation, Picosecond phenomena, Phase modulation, Glasses, Pulsed laser operation, Complex systems, Laser energy, Diffraction gratings, Nonlinear optics

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Proceedings Article | 14 August 1997 Paper

Terawatt short-pulse CPA Nd:glass laser

Jan Badziak, Sergey Chizhov, Aleksey Kozlov, Jozef Makowski, Marian Paduch, Krzysztof Tomaszewski, Alexander Vankov, Vladimir Yashin

Proceedings Volume 3186, (1997) https://doi.org/10.1117/12.280507

KEYWORDS: Neodymium glass lasers, Fiber amplifiers, Fiber lasers

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Proceedings Article | 4 April 1997 Paper

Optical breakdown of transparent dielectrics by picosecond and subnanosecond laser pulses

Aleksey Kozlov, Alexander Andreev, Sergey Chizhov, Alexander Vankov, Vladimir Yashin

Proceedings Volume 3093, (1997) https://doi.org/10.1117/12.271660

KEYWORDS: Picosecond phenomena, Laser damage threshold, Dielectrics, Optical amplifiers, Electrons, Silica, Diffraction gratings, Pulsed laser operation, Oscillators, Plasma

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Proceedings Article | 12 April 1996 Paper

Absorption of ultrashort laser pulses, x-ray and fast-particle generation in superdense plasma

Alexander Andreev, Valentin Bayanov, Alexander Vankov, Aleksey Kozlov, Vladimir Komarov, I. Kurnin, Nikita Solovyov, Sergey Chizhov, Vladimir Yashin, Jiri Limpouch

Proceedings Volume 2770, (1996) https://doi.org/10.1117/12.238025

KEYWORDS: Plasma, Absorption, Ions, Laser energy, X-rays, Particles, Polarization, Aluminum, Picosecond phenomena, Pulsed laser operation

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Proceedings Article | 10 August 1994 Paper

1-TW Nd:glass laser system

Alexander Vankov, Aleksey Kozlov, Sergey Chizhov, Vladimir Yashin

Proceedings Volume 2095, (1994) https://doi.org/10.1117/12.183079

KEYWORDS: Laser systems engineering, Pulsed laser operation, Optical amplifiers, Diffraction gratings, Picosecond phenomena, Neodymium glass lasers, Glasses, Amplifiers, Physics, Oscillators

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