Mr. Carlos Eduardo Osornio Martínez Profile

Carlos Eduardo Osornio Martínez

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Publications (4)

Proceedings Article | 13 March 2024 Presentation

High gain erbium doped aluminium oxide waveguide amplifiers integrated with silicon nitride circuits in a multi-layer platform

Dawson Bonneville, Carlos Osornio-Martínez, Ivo Hegeman, Meindert Dijkstra, Sonia García-Blanco

Proceedings Volume PC12889, PC1288906 (2024) https://doi.org/10.1117/12.3004710

KEYWORDS: Waveguides, Aluminum oxide, Silicon nitride, Erbium, Wavelength division multiplexing, Sputter deposition, Silicon, Quantum photonics, Ions, Telecommunications

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Proceedings Article | 30 May 2022 Presentation

On-chip photonics erbium-doped amplifiers: fabrication and characterization of Al2O3:Er3+ and development as a laser platform

Dawson Bonneville, Ward Hendriks, Carlos Osornio-Martínez, Sohelia Mardani, Kai Wang, Anne Dijkstra, Sonia García-Blanco

Proceedings Volume PC12142, PC121420J (2022) https://doi.org/10.1117/12.2624950

KEYWORDS: Optical amplifiers, Laser development, Photonics, Waveguides, Silicon, Integrated optics, Photonic integrated circuits, Optics manufacturing, Ions, Wavelength division multiplexing

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Proceedings Article | 18 April 2021 Presentation

Monolithic active-passive photonic integration

Sonia García-Blanco, Ivo Hegeman, Jinfeng Mu, Carlijn M. van Emmerik, Carlos Osornio Martinez, Meindert Dijkstra

Proceedings Volume 11775, 117750A (2021) https://doi.org/10.1117/12.2589271

KEYWORDS: Integrated optics, Active optics, Tolerancing, Titanium dioxide, Photonic integrated circuits, Optical amplifiers, Integrated photonics, Integrated circuits, Integrated circuit design

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Proceedings Article | 5 September 2018 Paper

Noninvasive detection of collagen regeneration after an isotretinoin treatment and ablative laser surgery in patients with acne scars by Raman spectroscopy

F. S. Chiwo González, E. Guevara, M. G. Ramírez-Elías, C. Castillo-Martínez, C. E. Osornio-Martínez, R. Cabrera-Alonso, Francisco Pérez-Atamoros, F. J. González

Proceedings Volume 10728, 107280M (2018) https://doi.org/10.1117/12.2320016

KEYWORDS: Collagen, Raman spectroscopy, Surgery, Laser therapeutics, Wound healing, Principal component analysis, Terahertz technology, Gas lasers, Skin, Ablative surgery

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Background: To the date, oral isotretinoin is the most effective treatment for acne scars, and by combining their use with an ablative surgery results in improving the effects of the skin restoration. However, it is highly recommended by dermatologists, to wait for a period of 6 months between the isotretinoin treatment and the laser surgery, and that relative high period of time can lead to negative effects like anxiety or psychological distress in the patients. Our objective is to demonstrate that combining an ablative laser surgery and an isotretinoin treatment at therapeutic doses improves the acne wound healing in a considerably short period of time in comparison with previous studies. Additionally, it is of our interest to evaluate the wound healing due the collagen regeneration by the use of Raman spectroscopy, recently used as a non-invasive medical tool for skin diseases. Method: The study was performed in 9 patients who underwent on an oral isotretinoin treatment due to the presence of acne scars on the face. All patients received one single treatment with a CO₂ Ablative Fractional Laser (AFL) on four zones of the face within a range of four weeks after isotretinoin treatment. Additionally, an untreated measurement in the elbow side of the arm acted as a control. Both treatments, the isotretinoin and the ablative surgery, were performed by the same dermatologist. The patients were evaluated by means of Raman spectroscopy before and after the treatment and for the data processing, two different statistical approaches were applied to the Raman spectra with the objective to assess the presence of a specific collagen type. Results: The patients showed normal wound healing post AFL treatments and it was shown that with a therapeutic dose of oral isotretinoin and with one single laser surgery in a relative short period of time, a collagen regeneration was observed. Conclusion: When combined AFL surgery and isotretinoin treatment at therapeutic doses, a regeneration of a type of collagen is observed, which is quantified non-invasively by Raman spectroscopy.

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