Many liver resection surgeries are performed with fluorescence-guided approaches using near-infrared (NIR) fluorescent dyes, such as indocyanine green (ICG), in an effort to prevent postoperative bile leakage. However, these existing fluorophores have limitations when assessing bile leakages and other bile duct injuries. We have reported a novel NIR fluorescent dye, BL-760, that we believe would be favorable over ICG and other NIR dyes during hepatectomies. We will describe our hepatic resection surgery study conducted with a swine model while comparing the advantages and disadvantages of common fluorescent dyes and the novel BL-760 dye.
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