Prof. Dieter Manstein Profile

Prof. Dieter Manstein

Assistant Professor at Massachusetts General Hospital

SPIE Involvement:

Author

Publications (22)

Proceedings Article | 13 March 2024 Presentation

Label-free visualization of far UV-C skin safety with dynamic optical coherence tomography with microscopic resolution (dmOCT)

Felix Hilge, Michael Wang-Evers, Lara Buhl, Heather Downs, Maron Dolling, Gereon Hüttmann, Reginald Birngruber, Dieter Manstein

Proceedings Volume PC12830, PC128302M (2024) https://doi.org/10.1117/12.3005568

KEYWORDS: Skin, Safety, Optical coherence tomography, Visualization, Ultraviolet radiation, Tissues, Biological imaging, Temporal resolution, Scattering, Radiation effects

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Proceedings Article | 17 March 2023 Presentation

Assessment of intrinsic and extrinsic aging on dermal morphology using optical coherence tomography

Vidyalakshmi Anilkumar, Felix Hilge, Timo Kepp, Michael Wang-Evers, Spencer Brush, Hinnerk Schulz-Hildebrandt, Gereon Hüttmann, Heinz Handels, Dieter Manstein

Proceedings Volume PC12352, PC123520D (2023) https://doi.org/10.1117/12.2650110

KEYWORDS: Optical coherence tomography, Skin, Shape analysis, Machine learning

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Proceedings Article | 17 March 2023 Presentation

Large area fractional laser treatment of mouse skin enhances the metabolic rate

Michael Wang-Evers, Nunciada Salma, Daniel Karasik, Armen Yerevanian, Heather Downs, Tuanlian Luo, Dieter Manstein

Proceedings Volume PC12352, PC123520J (2023) https://doi.org/10.1117/12.2649996

KEYWORDS: Skin, Laser therapeutics, Tissues, Mouse models, Laser development, Injuries, Inflammation, Blood, Biological research

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Proceedings Article | 6 March 2023 Presentation

A phosphorescent microneedle array for measurement of oxygen partial pressure in tissue

Matthias Müller, Juan Pedro Cascales Sandoval, Haley Marks, Michael Wang-Evers, Dieter Manstein, Conor Evans

Proceedings Volume PC12375, PC1237505 (2023) https://doi.org/10.1117/12.2649485

KEYWORDS: Oxygen, Tissues, Skin, Phosphorescence, Blood, Tissue optics, Oximetry, Ischemia, Heart, Electrodes

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Proceedings Article | 7 March 2022 Presentation

Effects on dynamic-microscopic OCT signals after manipulation of keratinocyte metabolism in an in-vitro skin model by temperature and with metabolic reagents

Felix Hilge, Hinnerk Schulz-Hildebrandt, Michael Wang-Evers, Nunciada Salma, Martin Ahrens, Michael Münter, Gereon Hüttmann, Reginald Birngruber, Dieter Manstein

Proceedings Volume PC11948, PC1194814 (2022) https://doi.org/10.1117/12.2612879

KEYWORDS: Optical coherence tomography, Skin, In vitro testing, Temperature metrology, Mode conditioning cables, Signal processing, Scattering, Acquisition tracking and pointing, 3D modeling, Motion models

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Proceedings Article | 7 March 2022 Presentation

Image analysis of topical drug uptake in tissue after ablative fractional laser treatment

Haley Marks, Sarfaraz Quadri, Joshua Glahn, Michael Wang-Evers, James Talton, Dieter Manstein

Proceedings Volume PC11938, PC1193807 (2022) https://doi.org/10.1117/12.2610180

KEYWORDS: Skin, Laser tissue interaction, Laser therapeutics, Image analysis, Luminescence, Injuries, Image segmentation, Ultraviolet radiation, Ultraviolet photography, Tissue optics

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Proceedings Article | 5 March 2021 Presentation

Subcutaneous injection of ICG for fractional thermal injury using an 808nm wide-area scanning laser diode

Haley Marks, Weeranut Phothong, Joshua Glahn, Tuanlian Luo, Garuna Kositratna, Dieter Manstein

Proceedings Volume 11618, 1161808 (2021) https://doi.org/10.1117/12.2578754

KEYWORDS: Injuries, Laser therapeutics, Indocyanine green, Skin, Diodes, Semiconductor lasers, Nanoparticles, Laser tissue interaction, Erbium lasers, YAG lasers

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Proceedings Article | 5 March 2021 Presentation

Novel method to assess the impact of aging and sun exposure on skin morphology by optical coherence tomography

Felix Hilge, Michael Evers, Malte Casper, Joshua Zev Glahn, Weeranut Phothong, Garuna Kositratna, Hinnerk Schulz-Hildebrandt, Gereon Hüttmann, Dieter Manstein

Proceedings Volume 11618, 116180A (2021) https://doi.org/10.1117/12.2577822

KEYWORDS: Skin, Optical coherence tomography, Sun, Radium, Surface properties, Detection and tracking algorithms, Dermatology, Data conversion

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Proceedings Article | 10 March 2020 Presentation

A luminescent oxygen-sensing hydrogel for mapping tissue oxygenation (Conference Presentation)

Haley Marks, Juan Pedro Cascales Sandoval, Joshua Glahn, Katherine Cook, Emmanuel Roussakis, Mark Grinstaff, Dieter Manstein, Conor Evans

Proceedings Volume 11256, 112560F (2020) https://doi.org/10.1117/12.2544561

KEYWORDS: Tissues, Oxygen, Skin, Lead, Imaging devices, Absorbance, Imaging systems, Molecules, Quantum efficiency, Visualization

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Proceedings Article | 6 March 2020 Presentation

Capillary refill: a technique for obtaining histology-grade OCT angiography maps of human dermal vasculature in vivo (Conference Presentation)

Michael Evers, Malte Casper, Garuna Kositratna, Josh Glahn, Weeranut Phothong, Tuanlian Luo, Dieter Manstein

Proceedings Volume 11211, 112110T (2020) https://doi.org/10.1117/12.2545086

KEYWORDS: Blood vessels, Image compression, Image segmentation, Capillaries, Skin, Optical coherence tomography, Angiography, In vivo imaging, Biopsy, Diagnostics

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Proceedings Article | 19 July 2019 Paper

Monitoring temperature induced phase changes in subcutaneous fatty tissue using an astigmatism corrected dynamic needle probe

H. Schulz-Hildebrandt, N. Meyer-Schell, M. Casper, M. Evers, R. Birngruber, D. Manstein, G. Hüttmann

Proceedings Volume 11073, 110730L (2019) https://doi.org/10.1117/12.2527087

KEYWORDS: Tissues, Monochromatic aberrations, Optical coherence tomography, Multimode fibers, Refractive index, Temperature metrology, Tissue optics, Scattering, Natural surfaces, Positron emission tomography

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SPIE Journal Paper | 30 April 2019 Open Access

Optimization-based vessel segmentation pipeline for robust quantification of capillary networks in skin with optical coherence tomography angiography

Malte Casper, Hinnerk Schulz-Hildebrandt, Michael Evers, Reginald Birngruber, Dieter Manstein, Gereon Hüttmann

JBO, Vol. 24, Issue 04, 046005, (April 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.4.046005

KEYWORDS: Image segmentation, Skin, Angiography, Capillaries, Optical coherence tomography, Image processing, Binary data, Denoising, Gaussian filters, Digital filtering

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Proceedings Article | 15 March 2018 Presentation

A non-invasive system to assess tissue temperature distribution (Conference Presentation)

Sahar Juhani, Reza Monazami, Dieter Manstien

Proceedings Volume 10510, 105100A (2018) https://doi.org/10.1117/12.2291354

KEYWORDS: Tissues, Laser tissue interaction, Mathematical modeling, Temperature metrology, Reliability, Laser therapeutics, Beam controllers, Natural surfaces, Structural design, Safety

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Proceedings Article | 14 March 2018 Presentation

Optimized segmentation and characterization of capillary networks using OCT (Conference Presentation)

Malte Casper, Hinnerk Schulz-Hildebrandt, Michael Evers, Reginald Birngruber, Dieter Manstein, Gereon Hüttmann

Proceedings Volume 10467, 1046707 (2018) https://doi.org/10.1117/12.2292005

KEYWORDS: Image segmentation, Optical coherence tomography, Skin, Capillaries, Angiography, 3D image processing, Image processing, Tissues, Machine vision, Computer vision technology

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Proceedings Article | 14 March 2018 Presentation

Phasor fluorescence lifetime microscopy of NADH to analyze metabolic activity of adipocytes (Conference Presentation)

Michael Evers, Nunciada Salma, Sam Osseiran, Malte Casper, Reginald Birngruber, Conor Evans, Dieter Manstein

Proceedings Volume 10498, 1049808 (2018) https://doi.org/10.1117/12.2289294

KEYWORDS: Luminescence, Fluorescence lifetime imaging, Multiphoton microscopy, Microscopy, Mode conditioning cables, Multiphoton fluorescence microscopy, Nondestructive evaluation, Oxygen

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Proceedings Article | 2 March 2018 Paper

Segmentation of subcutaneous fat within mouse skin in 3D OCT image data using random forests

Timo Kepp, Christine Droigk, Malte Casper, Michael Evers, Nunciada Salma, Dieter Manstein, Heinz Handels

Proceedings Volume 10574, 1057426 (2018) https://doi.org/10.1117/12.2290085

KEYWORDS: Image segmentation, Optical coherence tomography, Skin, 3D image processing, Medical imaging, Image processing algorithms and systems, Feature extraction

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Proceedings Article | 24 April 2017 Presentation

A new and highly sensitive method of analyzing metabolic activity using FLIM (Conference Presentation)

Michael Evers, Nunciada Salma, Reginald Birngruber, Conor Evans, Dieter Manstein

Proceedings Volume 10069, 100691O (2017) https://doi.org/10.1117/12.2252339

KEYWORDS: Glucose, Fluorescence lifetime imaging, Mode conditioning cables, Luminescence, Microscopy, Two photon excitation microscopy, Information visualization, Visualization, Tissues, Proteins

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Proceedings Article | 19 April 2017 Presentation

Imaging cold-induced vasodynamic behaviour in skin using OCT for microangiography (Conference Presentation)

Malte Casper, Hinnerk Schulz-Hildebrandt, Michael Evers, Cuc Nguyen, Reginald Birngruber, Gereon Hüttmann, Dieter Manstein

Proceedings Volume 10037, 100370S (2017) https://doi.org/10.1117/12.2251485

KEYWORDS: Optical coherence tomography, Dermatology, Skin, Spatial resolution, Angiography, Physiology, 3D image processing, Temperature metrology, Blood vessels, Speckle

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Proceedings Article | 19 April 2017 Presentation

Measuring temperature induced phase change kinetics in subcutaneous fatty tissues using near infrared spectroscopy, magnetic resonance imaging and optical coherence tomography (Conference Presentation)

Amir Sajjadi, Stefan Carp, Dieter Manstein

Proceedings Volume 10037, 100370M (2017) https://doi.org/10.1117/12.2250898

KEYWORDS: Crystals, Near infrared spectroscopy, Tissues, Optical coherence tomography, Scattering, Tissue optics, Temperature metrology, Spectroscopy, Skin, Magnetic resonance imaging

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SPIE Journal Paper | 6 February 2014 Open Access

Photosensitizer fluorescence and singlet oxygen luminescence as dosimetric predictors of topical 5-aminolevulinic acid photodynamic therapy induced clinical erythema

Srivalleesha Mallidi, Sriram Anbil, Seonkyung Lee, Dieter Manstein, Stefan Elrington, Garuna Kositratna, David Schoenfeld, Brian Pogue, Steven Davis, Tayyaba Hasan

JBO, Vol. 19, Issue 02, 028001, (February 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.2.028001

KEYWORDS: Luminescence, Photodynamic therapy, Picosecond phenomena, Oxygen, Skin, Statistical analysis, Photography, Tissue optics, In vivo imaging, Signal detection

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Proceedings Article | 24 June 1993 Paper

Technical features for the clinical use of the 193-nm excimer laser

Werner Foerster, P. Nordmeyer, Dieter Manstein, Martin Schuerenberg

Proceedings Volume 1877, (1993) https://doi.org/10.1117/12.147559

KEYWORDS: Excimer lasers, Cornea, Laser vision correction, Laser therapeutics, Laser systems engineering, Surgery, Laser ablation, Beam delivery, Eye, Monochromatic aberrations

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Proceedings Article | 24 June 1993 Paper

Qualitative holographic-interferometric analysis of T-incisions of different length in vitro-A preliminary report

Werner Foerster, Henryk Kasprzak, Dieter Manstein, Gert von Bally, H. Busse

Proceedings Volume 1877, (1993) https://doi.org/10.1117/12.147519

KEYWORDS: Holography, Fringe analysis, Cornea, Holographic interferometry, Eye, Surgery, Interferometry, Image classification, Protactinium, Monochromatic aberrations

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Showing 5 of 22 publications

Conference Committee Involvement (2)

Therapeutic Laser Applications and Laser-Tissue Interactions

18 June 2007 | Munich, Germany

Therapeutic Laser Applications and Laser-Tissue Interactions II

12 June 2005 | Munich, Germany

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