Lab-on-Fiber (LoF) technology is a research field aimed at transforming a simple optical fiber into a multifunctional probe, which exploits enhanced light-matter interaction for a variety of applications, with special aptitude for biosensing. An attractive thread in this scenario is the integration of plasmonic metasurfaces onto an optical fiber tip, known as optical fiber “meta-tips”, leading to the development of a new generation of highly sensitive optrodes. Here we report on the latest achievements concerning the investigation of LoF probes assisted by plasmonic phase-gradient metasurfaces for the detection of small molecules as well as clinically relevant cancer biomarkers in the picomolar range. The high biosensing performance, joined with huge potential for miniaturization and integration, makes this platform an excellent candidate for the development of Point-of-Care (PoC) devices aimed at real-time and label-free detection of clinically relevant biomarkers offering several advantages over conventional procedures.
This contribution deals with a feasibility analysis for the development of fiber optic humidity sensors to be applied in high-energy physics (HEP) experiments currently running at the European Organization for Nuclear Research (CERN).In particular, due to the wide investigations carried out in the last years aimed to assess the radiation hardness capability of fiber optic technology in HEP environments, our multidisciplinary research group has been recently engaged in the development of high-sensitivity TiO2-coated Long Period Fiber Gratings (LPGs) sensors for relative humidity (RH) monitoring at temperatures below 0°C as well as in presence of strong ionizing radiations.
This work investigates the performances and the radiation hardness capability of optical thermo-hygrometers based on Fiber Bragg Gratings (FBG) technology for humidity monitoring in the Compact Muon Solenoid experiment (CMS) at CERN, in Geneva. Extensive characterizations in terms of sensitivity, repeatability and accuracy on 80 specially produced polyimide-coated FBG sensors and 80 commercial temperature FBG sensors are presented. Progressive irradiation campaigns with γ- ionizing radiations were also performed. Results showed that the sensors sensitivity is unchanged after each radiation exposure; while the wavelength peak exhibits a radiation-induced shift. The saturation properties of this shift are discussed.
This contribution deals with a feasibility analysis for the development of radiation tolerant fiber optic humidity sensors based on long period grating (LPG) technology to be applied in high-energy physics (HEP) experiments currently running at the European Organization for Nuclear Research (CERN). In particular, here we propose a high-sensitivity LPG sensor coated with a finely tuned titanium dioxide (TiO2) thin layer (~100 nm thick) through the sol gel deposition method. The sensor characterization in the relative humidity (RH) range [0-75] % at four different temperatures (in the range -10°C - 25°C) was carried out to assess sensor performances in real operative conditions required in typical experiments running at CERN. Experimental results demonstrate the very high RH sensitivities of the proposed device (up to 1.4 nm/%RH in correspondence of very low humidity levels), which turned out to be from one to three orders of magnitudes higher than those exhibited by fiber Bragg grating (FBG) sensors coated with micrometer thin polyimide overlays. The radiation tolerance capability of the TiO2-coated LPG sensor is also investigated by comparing the sensing performances before and after its exposure to 1Mrad dose of γ-ionizing radiation. Collected results demonstrate the strong potentialities of the proposed technology in light of its future exploitation in HEP applications as robust and valid alternative to currently used commercial hygrometers.
We report on a feasibility analysis for the development of fiber optic humidity sensors to be applied in high-energy physics applications and in particular in experiments actually running at the European Organization for Nuclear Research (CERN). Due to the stringent sensors requirements concerning radiation hardness capability and low temperature operation, we focus our attention on the investigation of fiber optic humidity sensors based on polyimmide (PI)-coated Fiber Bragg Gratings (FBGs). Data here reported, obtained during a wide experimental campaign carried out in the laboratories of CERN, demonstrate that the selected technological platform is able to perform relative humidity (RH) measurements with percent resolution in the temperature range -15-20°C as well as in presence of ionizing radiations up to 10KGray, largely outperforming conventional humidity sensors, currently employed within CERN environment.
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