KEYWORDS: Control systems, Temperature metrology, Human-machine interfaces, Fluctuations and noise, Control systems design, Analytical research, Computing systems, Process control, Telecommunications, Computer architecture
Effective host-local system architecture for PCR chips is presented. The functions required for the control of the chips
and their partitioning into the host and the local system are qualitatively analyzed. The results indicated that, most
functions can be resided in the host to deliver the benefits on the development period, the system cost, and the
maintenance. The control system was implemented with PC as the host and the local system was connected by USB
interface, obtaining the superior development and the GUI design environment. A PCB-based PCR chip example was
constructed and tested to verify the proposed system.
Template matching method is presented to identify the peaks from the scanned signals of lateral flow immunoassay
strips. The template is composed of two pulses separated by the distance of the control and the target ligand line in the
assay, and is convolved with the scanned signal to deliver the maximum at the center of the two peaks. The peak regions
were identified with the predefined distances from the center. Glycosylated haemoglobin immunoassay strips and
fluorescent strip readers from Boditechmed Inc. were tested to estimate the lot and reader variations of the concentration
measurands. The results showed the robustness of the propose method.
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