Terahertz (THz) wave has significant potential in label-free biomedical diagnosis because of its fingerprint spectrum and noninvasive and nonionizing properties to living organisms. Here, a transmission continuous-wave THz spectroscopy system was used to measure 3 groups of human cancerous and normal ovarian tissues. Fresh tissue samples were made into paraffin-embedded tissue sections with a thickness of 1-2 mm, and the THz transmittance spectra of these samples were obtained in the 0.4-1.5 THz range. These results indicate that cancerous ovarian tissues have a higher THz absorption compared with normal ones. The absorption peaks at 0.588, 0.748 and 0.812 THz of normal ovarian tissue get weaker and even disappear in the transmittance line of serous ovarian cancer tissue, while the absorption peak at 1.396 THz get enhanced. Our preliminary results demonstrate the promise of continuous-wave THz spectroscopy technology in label-free ovarian cancer detection.
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