Dr. Justinas Ceponkus Profile

Dr. Justinas Ceponkus

at Vilnius Univ

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Author

Publications (11)

SPIE Journal Paper | 28 April 2023 Open Access

Fast and label-free intraoperative discrimination of malignant pancreatic tissue by attenuated total reflection infrared spectroscopy

Rimante Bandzeviciute, Gerald Steiner, Katja Liedel, Jonas Golde, Edmund Koch, Thilo Welsch, Christoph Kahlert, Daniel E. Stange, Marius Distler, Jürgen Weitz, Justinas Ceponkus, Valdas Sablinskas, Christian Teske

JBO, Vol. 28, Issue 04, 045004, (April 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.4.045004

KEYWORDS: Tissues, Tumors, Biological samples, Infrared spectroscopy, Resection, Spectroscopy, Attenuated total reflectance, Surgery, Crystals, Germanium

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Proceedings Article | 6 March 2023 Poster + Paper

Fiber-based ATR-IR spectroscopy for an intraoperative diagnosis of normal pancreatic tissue, pancreatitis, and malignant pancreatic lesions

Rimante Bandzeviciute, Gerald Steiner, Katja Liedel, Jonas Golde, Edmund Koch, Thilo Welsch, Christoph Kahlert, Daniel Stange, Marius Distler, Jürgen Weitz, Justinas Ceponkus, Valdas Sablinskas, Christian Teske

Proceedings Volume 12368, 123680H (2023) https://doi.org/10.1117/12.2647405

KEYWORDS: Tissues, Tumors, Infrared spectroscopy, Resection, Spectroscopy, Biological samples, Surgery, Attenuated total reflectance, Education and training

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Proceedings Article | 20 February 2018 Presentation + Paper

In situ detection of cancerous kidney tissue by means of fiber ATR-FTIR spectroscopy

Valdas Sablinskas, Martynas Velicka, Milda Pucetaite, Vidita Urboniene, Justinas Ceponkus, Rimante Bandzeviciute, Feliksas Jankevicius, Tatiana Sakharova, Olga Bibikova, Gerald Steiner

Proceedings Volume 10497, 1049713 (2018) https://doi.org/10.1117/12.2289393

KEYWORDS: Tissues, Spectroscopy, Kidney, Tissue optics, Cancer, Sensors, FT-IR spectroscopy, Infrared spectroscopy, Tumors

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The crucial goal of kidney-sparing surgical resection of a malignant tumor is complete removal of the cancerous tissue. The exact border between the cancerous and normal tissues is not always possible to identify by naked eye, therefore, a supplementary intraoperative diagnosis is needed. Unfortunately, intraoperative pathology methods used nowadays are time consuming and of inadequate quality rendering not definitive diagnosis. It has recently been shown that ATR-FTIR spectroscopy can be used for fast discrimination between cancerous and normal kidney tissues by analyzing the collected spectra of the tissue touch imprint smears. Most prominent differences are obtained in the wavenumber region from 950 cm^-1 to 1250 cm^-1, where the spectral bands due to the molecular vibrations of glycogen arise in the spectra of cancerous tissue smears. Such method of detection of cancerous tissue is limited by requirement to transfer the suspected tissue from the body to the FTIR instrument and stamp it on an ATR crystal of the spectrometer. We propose a spectroscopic tool which exploits the same principle of detection of cancerous cells as mentioned above, but does not require the tissue to be transferred from the body to the spectrometer. The portable spectrometer used in this design is equipped with fiber ATR probe and a sensitive liquid nitrogen cooled MCT detector. The design of the fiber probe allows the ATR tip to be changed easily in order to use only new sterilized tips for each measurement point of the tissue. It also enables sampling multiple areas of the suspected tissue with high lateral resolution which, in turn, increases accuracy with which the marginal regions between normal and cancerous tissues can be identified. Due to the loss of optical signal in the fiber probe the spectra have lower signal-to-noise ratio than in the case of standard ATR sampling setup. However, software for the spectral analysis used with the fiber probe design is still able to distinguish between cancerous and normal tissues with high accuracy.

Proceedings Article | 16 February 2017 Paper

Assignment of vibrational spectral bands of kidney tissue by means of low temperature SERS spectroscopy

M. Velicka, M. Radzvilaite, J. Ceponkus, V. Urboniene, M. Pucetaite, F. Jankevicius, G. Steiner, V. Sablinskas

Proceedings Volume 10068, 100681W (2017) https://doi.org/10.1117/12.2252907

KEYWORDS: Surface enhanced Raman spectroscopy, Tissues, Kidney, Raman spectroscopy, Cancer, Molecules, Nanoparticles, Silver, Spectroscopy

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Proceedings Article | 7 March 2016 Presentation + Paper

Intra-operative on-line discrimination of kidney cancer from normal tissue by IR ATR spectroscopy of extracellular fluid

V. Urboniene, M. Velicka, J. Ceponkus, M. Pucetaite, F. Jankevicius, V. Sablinskas, G. Steiner

Proceedings Volume 9704, 97040E (2016) https://doi.org/10.1117/12.2213408

KEYWORDS: Tissues, Kidney, Cancer, Absorption, Infrared spectroscopy, Tissue optics, Surgery, Attenuated total reflectance, Principal component analysis, Spectroscopy

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Proceedings Article | 16 September 2015 Paper

Study of single walled carbon nanotube functionalization by means of surface enhanced Raman spectroscopy

Justinas Ceponkus, Martynas Velicka, Milda Pucetaite, Valdas Sablinskas

Proceedings Volume 9552, 955213 (2015) https://doi.org/10.1117/12.2186223

KEYWORDS: Nanoparticles, Raman spectroscopy, Silver, Surface enhanced Raman spectroscopy, Single walled carbon nanotubes, Chemical species, Carbon nanotubes, Prisms, Particles, Spherical lenses

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Proceedings Article | 21 August 2015 Paper

Detection of cancerous biological tissue areas by means of infrared absorption and SERS spectroscopy of intercellular fluid

M. Velicka, V. Urboniene, J. Ceponkus, M. Pucetaite, F. Jankevicius, V. Sablinskas

Proceedings Volume 9550, 95500A (2015) https://doi.org/10.1117/12.2186395

KEYWORDS: Tissues, Surface enhanced Raman spectroscopy, Kidney, Absorption, Tissue optics, Infrared spectroscopy, Spectroscopy, Raman spectroscopy, Microfluidics, Surgery

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Proceedings Article | 18 June 2013 Paper

Baseline correction of infrared absorption spectra of urinary sediments by taking mie scattering effects into account

S. Tamosaityte, E. Baltakyte, D. Blazevic, M. Pucetaite, J. Ceponkus, V. Hendrixson, S. Varvuolyte, V. Sablinskas

Proceedings Volume 8798, 87980V (2013) https://doi.org/10.1117/12.2032508

KEYWORDS: Mie scattering, Infrared radiation, Crystals, Absorption, Infrared spectroscopy, Scattering, Calcium, Chemical analysis, Renal calculi, Microscopy

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SPIE Journal Paper | 1 September 2011 Open Access

Infrared spectroscopic imaging of renal tumor tissue

Valdas Sablinskas, Vidita Urboniene, Justinas Ceponkus, Arvydas Laurinavicius, Darius Dasevicius, Feliksas Jankevicius, Vaiva Hendrixson, Edmund Koch, Gerald Steiner

JBO, Vol. 16, Issue 09, 096006, (September 2011) https://doi.org/10.1117/12.10.1117/1.3622292

KEYWORDS: Tumors, Tissues, Tissue optics, Spectroscopy, Imaging spectroscopy, Infrared spectroscopy, FT-IR spectroscopy, Infrared imaging, Infrared radiation, Absorbance

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Proceedings Article | 23 February 2011 Paper

Infrared spectroscopic imaging of kidney tumor tissue

V. Sablinskas, G. Steiner, E. Koch, J. Ceponkus, M. Pucetaite, S. Strazdaite, V. Urboniene, F. Jankevicius

Proceedings Volume 7902, 790221 (2011) https://doi.org/10.1117/12.875258

KEYWORDS: Infrared spectroscopy, Infrared imaging, Spectroscopy, Imaging spectroscopy, Tissues, Tumors, Infrared radiation, Kidney, Tissue optics, Sensors

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Proceedings Article | 21 February 2008 Paper

Infrared spectroscopic imaging with high spatial resolution and high sensitivity

Valdas Sablinskas, Gerald Steiner, Justinas Ceponkus, Reiner Salzer

Proceedings Volume 6869, 68690X (2008) https://doi.org/10.1117/12.768977

KEYWORDS: Free electron lasers, Spectroscopy, Infrared radiation, Molecules, Gold, Infrared spectroscopy, Infrared imaging, Spatial resolution, Mirrors, FT-IR spectroscopy

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Showing 5 of 11 publications

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