Prof. Karl H. Schoenbach Profile

Prof. Karl H. Schoenbach

Eminent Professor at Old Dominion Univ

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Publications (22)

Proceedings Article | 23 February 2013 Paper

Neurostimulation using subnanosecond electric pulses

Shu Xiao, Andrei Pakhomov, Fei Guo, Swetha Polisetty, Karl Schoenbach

Proceedings Volume 8585, 85850M (2013) https://doi.org/10.1117/12.2003341

KEYWORDS: Tissues, Dielectrics, Antennas, Action potentials, Neurons, Brain, Reflectors, Signal attenuation, Head, Picosecond phenomena

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Proceedings Article | 25 May 2006 Paper

Neuromuscular disruption with ultrashort electrical pulses

Andrei Pakhomov, Juergen Kolb, Ravindra Joshi, Karl Schoenbach, Thomas Dayton, James Comeaux, John Ashmore, Charles Beason

Proceedings Volume 6219, 621903 (2006) https://doi.org/10.1117/12.665617

KEYWORDS: Pulsed energy weapons, Electrodes, Pulse generators, Skin, Ultrafast phenomena, Calcium, Safety, Organisms, Thermal effects, Switches

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Proceedings Article | 1 April 2005 Paper

Dynamic effects and applications for nanosecond pulsed electric fields in cells and tissues

Stephen Beebe, Peter Blackmore, Emily Hall, Jody White, Lauren Willis, Laura Fauntleroy, Juergen Kolb, Karl Schoenbach

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.604449

KEYWORDS: Calcium, Phase modulation, Cell death, Picosecond phenomena, Tissues, Luminescence, Colon, Tumors, In vivo imaging, Green fluorescent protein

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Nanosecond, high intensity pulsed electric fields [nsPEFs] that are below the plasma membrane [PM] charging time constant have decreasing effects on the PM and increasing effects on intracellular structures and functions as the pulse duration decreases. When human cell suspensions were exposed to nsPEFs where the electric fields were sufficiently intense [10-300ns, ≤300 kV/cm.], apoptosis signaling pathways could be activated in several cell models. Multiple apoptosis markers were observed in Jurkat, HL-60, 3T3L1-preadipocytes, and isolated rat adipocytes including decreased cell size and number, caspase activation, DNA fragmentation, and/or cytochrome c release into the cytoplasm. Phosphatidylserine externalization was observed as a biological response to nsPEFs in 3T3-L1 preadipocytes and p53-wildtype and -null human colon carcinoma cells. B10.2 mouse fibrosarcoma tumors that were exposed to nsPEFs ex vivo and in vivo exhibited DNA fragmentation, elevated caspase activity, and reduced size and weight compared to contralateral sham-treated control tumors. When nsPEF conditions were below thresholds for apoptosis and classical PM electroporation, non-apoptotic responses were observed similar to those initiated through PM purinergic receptors in HL-60 cells and thrombin in human platelets. These included Ca²⁺ mobilization from intracellular stores [endoplasmic reticulum] and subsequently through store-operated Ca²⁺ channels in the PM. In addition, platelet activation measured as aggregation responses were observed in human platelets. Finally, when nsPEF conditions followed classical electroporation-mediated transfection, the expression intensity and number of GFP-expressing cells were enhanced above cells exposed to electroporation conditions alone. These studies demonstrate that application of nsPEFs to cells or tissues can modulate cell-signaling mechanisms with possible applications as a new basic science tool, cancer treatment, wound healing, and gene therapy.

Proceedings Article | 1 April 2005 Paper

Real-time imaging of membrane potentials during exposure to nanosecond pulsed electric fields

Juergen Kolb, Wolfgang Frey, Jody White, R. Price, Peter Blackmore, Stephen Beebe, Ravindra Joshi, Karl Schoenbach

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.591313

KEYWORDS: Luminescence, Pulsed laser operation, Molecules, Electrodes, Temporal resolution, Real time imaging, Microscopes, Cameras, Plasma, CCD cameras

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Proceedings Article | 10 June 2002 Paper

Basic research on pulsed power for narrowband high-power microwave sources

Edl Schamiloglu, Karl Schoenbach, Robert Vidmar

Proceedings Volume 4720, (2002) https://doi.org/10.1117/12.469831

KEYWORDS: Dielectrics, Liquids, Switches, Pulsed power, High power microwaves, Ceramics, Solids, Basic research, Microwave radiation, Carbonates

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Proceedings Article | 19 March 2002 Paper

Vacuum ultraviolet spectroscopy of microhollow cathode discharge plasmas

Kurt Becker, Peter Kurunczi, Mohamed Moselhy, Karl Schoenbach

Proceedings Volume 4460, (2002) https://doi.org/10.1117/12.459402

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Proceedings Article | 3 March 1995 Paper

Effect of submicrosecond electric fields on microorganisms: experiments and applications

Karl Schoenbach, Frank Peterkin, S. Beebe, D. Byars, R. Alden, P. Adolphson, T. Turner

Proceedings Volume 2374, (1995) https://doi.org/10.1117/12.205008

KEYWORDS: Bacteria, Microorganisms, Organisms, Capacitance, Cooling systems, Oceanography, Water, Information operations, Medical research, Energy efficiency

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Proceedings Article | 3 March 1995 Paper

Present status of the bistable optically controlled semiconductor switch (BOSS)

Frank Peterkin, Karl Schoenbach, Roger Dougal

Proceedings Volume 2374, (1995) https://doi.org/10.1117/12.205000

KEYWORDS: Switches, Gallium arsenide, Electrons, Semiconductors, Switching, Semiconductor lasers, Optical semiconductors, Silicon, Picosecond phenomena, Absorption

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Proceedings Article | 4 January 1995 Paper

Supralinear photoconductivity of copper-doped gallium arsenide

Karl Schoenbach, Ravindra Joshi, Frank Peterkin

Proceedings Volume 2343, (1995) https://doi.org/10.1117/12.198667

KEYWORDS: Copper, Gallium arsenide, Laser energy, Switching, Electrons, Switches, Semiconductors, Absorption, Silicon, Photoresistors

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Proceedings Article | 1 April 1994 Paper

Spatially resolved electron-beam induced current transient spectroscopy for deep-center characterization of diamond

Karl Schoenbach, T. Tessnow, Ravindra Joshi, Randy Roush, Ralf Brinkmann

Proceedings Volume 2151, (1994) https://doi.org/10.1117/12.171763

KEYWORDS: Diamond, Electrons, Semiconductors, Spectroscopy, Absorption, Electronics, Electron beams, Physical research, Dielectrics, Spatial resolution

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Proceedings Article | 9 June 1993 Paper

Development of current filaments in photoconductive GaAs switches

Karl Schoenbach, J. Kenney, Frank Peterkin, R. Allen

Proceedings Volume 1873, (1993) https://doi.org/10.1117/12.146554

KEYWORDS: Switches, Gallium arsenide, Absorption, Pulsed laser operation, Aluminum, Laser damage threshold, Switching, Optical diagnostics, Laser beam diagnostics, Semiconductor lasers

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Proceedings Article | 9 June 1993 Paper

Sudden breakdown of bulk semiconductor switches

Ralf Brinkmann, Karl Schoenbach, David Stoudt, Randy Roush

Proceedings Volume 1873, (1993) https://doi.org/10.1117/12.146544

KEYWORDS: Switches, Magnetism, Switching, Ionization, Semiconductors, Diffusion, Dielectrics, Information operations, Optical semiconductors, Electrons

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Proceedings Article | 12 May 1992 Paper

Optical measurements of the electric field and temperature distribution in photoconductive GaAs switches

Karl Schoenbach, J. Kenney, R. Allen

Proceedings Volume 1632, (1992) https://doi.org/10.1117/12.59058

KEYWORDS: Switches, Absorption, Gallium arsenide, Temperature metrology, Switching, Pulsed laser operation, Semiconductors, CCD cameras, Nd:YAG lasers, Silicon

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Proceedings Article | 12 May 1992 Paper

Electron-beam-activated zinc selenide and diamond switches

Karl Schoenbach, Mark Kennedy, Ravindra Joshi, Ralf Brinkmann, Ping-Tong Ho

Proceedings Volume 1632, (1992) https://doi.org/10.1117/12.59072

KEYWORDS: Switches, Diamond, Crystals, Semiconductors, Zinc, Switching, Gallium arsenide, Electrons, Resistance, Silicon

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Proceedings Article | 12 May 1992 Paper

Modeling of electron-beam-controlled diamond switches

Ralf Brinkmann, Karl Schoenbach

Proceedings Volume 1632, (1992) https://doi.org/10.1117/12.59076

KEYWORDS: Switches, Diamond, Switching, Dielectrics, Ionization, Semiconductors, Mathematical modeling, Device simulation, Pulsed power, Resistance

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Proceedings Article | 12 May 1992 Paper

Analysis of time-dependent current transport in an optically controlled Cu-compensated GaAs switch

Ralf Brinkmann, Karl Schoenbach, Michael Mazzola, Randy Roush, David Stoudt

Proceedings Volume 1632, (1992) https://doi.org/10.1117/12.59078

KEYWORDS: Switches, Pulsed laser operation, Switching, Gallium arsenide, Data modeling, Semiconductors, Instrument modeling, Silicon, Copper, Pulsed power

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Proceedings Article | 1 April 1991 Paper

Breakdown in pulsed-power semiconductor switches

Rudolf Germer, Joachim Mohr, Karl Schoenbach

Proceedings Volume 1358, (1991) https://doi.org/10.1117/12.23996

KEYWORDS: Semiconductors, Switches, Diodes

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Proceedings Article | 1 March 1991 Paper

Energy-level structure and electron transitions of GaAs:Cr optoelectronic materials

Hans-Joachim Schulz, Karl Schoenbach, B. Kimpel, Ralf Brinkmann

Proceedings Volume 1361, (1991) https://doi.org/10.1117/12.24299

KEYWORDS: Optoelectronics, Ions, Chromium, Gallium arsenide, Image processing, Oxidation

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Proceedings Article | 1 March 1991 Paper

Photoquenching and characterization studies in a bulk optically controlled GaAs semiconductor switch

Vishnu Lakdawala, Karl Schoenbach, Randy Roush, Gordon Barevadia, Michael Mazzola

Proceedings Volume 1378, (1991) https://doi.org/10.1117/12.25061

KEYWORDS: Gallium arsenide, Switches, Copper, Switching, Silicon, Diffusion, Electrons, Semiconductors, Data modeling, Spectroscopy

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Proceedings Article | 1 March 1991 Paper

High-power switching with electron-beam-controlled semiconductors

Ralf Brinkmann, Karl Schoenbach, Randy Roush, David Stoudt, Vishnu Lakdawala, Glenn Gerdin

Proceedings Volume 1378, (1991) https://doi.org/10.1117/12.25054

KEYWORDS: Switches, Semiconductors, Switching, Electrons, Gallium arsenide, Resistance, Doping, Picosecond phenomena, Copper, Electron beams

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Proceedings Article | 1 March 1991 Paper

Equilibrium and nonequilibrium properties of semiconductors with multiply ionizable deep centers

Ralf Brinkmann, Karl Schoenbach, Hans-Joachim Schulz

Proceedings Volume 1361, (1991) https://doi.org/10.1117/12.24401

KEYWORDS: Semiconductors, Thermodynamics, Crystals, Ionization, Chromium, Gallium arsenide, Optoelectronic devices, Doping, Process modeling, Phonons

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Proceedings Article | 1 February 1991 Paper

Deep-level configuration of GaAs:Si:Cu: a material for a new type of optoelectronic switch

Karl Schoenbach, Hans-Joachim Schulz, Vishnu Lakdawala, B. Kimpel, Ralf Brinkmann, Rudolf Germer, Gordon Barevadia

Proceedings Volume 1362, (1991) https://doi.org/10.1117/12.24476

KEYWORDS: Switches, Copper, Gallium arsenide, Optoelectronic devices, Silicon, Optoelectronics, Physics, Pulsed laser operation, Ionization, Data modeling

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Showing 5 of 22 publications

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