Age-related macular degeneration (AMD) is the leading cause of permanent vision loss and visual impairment in people over 60. Early detection of the disease is essential to prevent the evolution of the disease into an advanced stage. An eye care specialist has to perform a dilated eye exam, fundoscopy, a visual acuity test, and fundus photography to determine if a patient has macular degeneration and the stage of the disease. Most of the equipment used nowadays in eye care clinics is equipped in one system with both fundus camera and OCT technology that provides more comprehensive clinical evaluations. In most countries the healthcare system suffers from a low doctor to patient ratio; due to it, diagnosis can become time-consuming and error-prone. To minimize this downfall, a computer-aided diagnosis (CAD) strategy is proposed using machine learning techniques to predict the presence of age-related macular degeneration using both OCT and fundus images. The computer-aided diagnosis (CAD) is using a portable device, Jetson TX2 board, a powerful AI computer device, to predict the presence of an abnormality in the retina. A dataset composed of three categories: normal retina, dry AMD, and wet AMD from both OCT and fundus images have been used to evaluate the performance of different neuronal networks. Cost reduction and system portability are implemented with the proposed system for point of care in ophthalmology applications.
The paper is mainly focused on assessing the local effects of climate change on biodiversity, especially within the conservation of native plant species, by using a wearable plant demonstrator for chlorophyll and growth rate monitoring. The wearable proof-of-concept is implemented with: a) blue fluorescent fiber and light diffusion fiber configuration, for chlorophyll monitoring and b) optical fiber bending measurements, proportional with growing rate of the leaf. The blue fluorescent fiber from the Industrial Optical Fiber-USA is used to monitor chlorophyll fluorescence (spectral analysis) under stimulated conditions produced with light diffusion fiber. Stimulated light is induced by the light coupled to the surface of the leaf to be analyzed, using the Corning Fibrance (LDF) light diffusion fiber. The blue fluorescent fiber-BFF (peak 460 nm) is lateral sensitive and the chlorophyll fluorescence spectrum is coupled to the fiber core. The LDF is placed on the leaf, near BFF. The chlorophyll fluorescence emission spectrum falls outside the absorption spectrum of the blue fluorophore of the doped fiber core BFF. The chlorophyll fluorescence will propagate along the fiber, adding a specific spectral response corresponding to the analyzed scenario. The spectral response reflects the change with the physiological state of the photosynthetic system.
The paper presents a photonic smart-probe, based on a fluorescent fiber, dedicated for the point-of-care periodontal examination. Globally, periodontal diseases are prevalent both in developing and developed countries and affect about 20-50% of global population. The handpiece of the pressure sensitive periodontal probe should provide the accurately measurement of the depth of a pyorrhea pocket in a human or animal gum. Clinical attachment level (CAL) is the new gold standard for the diagnosis and monitoring of the periodontal disease. CAL has stimulated the recent introduction of novel periodontal probes. For point-of-care, a general dental practitioner usually uses low-cost first- or secondgeneration probes. They would require a low-cost smart-device (at least third-generation level), for accurate quick test results, light weight and easy to use, to avoid the wrong measurements. The proposed device is based on fluorescent linear optical fiber position sensor, adapted to the second-generation probe system. A modified surgical caliper with periodontal probe attachments, transforms the unit depth (mm-scale) of the probe into the cm-scale (according with the excitation length of the fluorescent fiber). The end of the fluorescent fiber is placed on the caliper scale and a SMD blue led attached to the caliper mobile arm is slid over the fluorescent fiber. The movable arm range is proportional with the mm depth of the periodontal probe into the gum. The T-Flame OceanOptics mini-spectrometer is used for signal processing. Lateral coupling of the excitation led light into the fluorescent fiber at different positions produces the emission spectral shift. Thus, the result of the energy transfer process changes for different lengths of the led excitation of the fluorescent fiber (at cm scale), as an overlap of the emission and absorption spectra of the PMMA co-doped fiber.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.