Mr. Miguel Caro Parrado Profile

Miguel Caro Parrado

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Proceedings Article | 3 January 2020 Paper

Characterizing local brain aging patterns in healthy subjects in structural magnetic resonance images

Miguel Caro, Diana Giraldo, Eduardo Romero

Proceedings Volume 11330, 113300O (2020) https://doi.org/10.1117/12.2542573

KEYWORDS: Brain, Binary data, Neuroimaging, Magnetism, Thalamus

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The purpose of this work is to characterize the process of natural neuronal death associated with brain aging in healthy subjects by characterizing local relationships in nuclear magnetic resonances. The whole method focuses on describing local neighborhoods with a texture descriptor, specifically the Linear Binary Pattern invariant to rotation, aiming to capture local tissue relationships by clustering this texture descriptor in brain regions previously parcelled. This approach has been tested in a group of control subjects extracted from the ADNI database project, dividing the experimental group after subjects’ chronological age. Results show differences concentrated in certain regions, i.e., the caudate, the hippocampus, and the thalamus, all of them usually reported as deteriorating with ageing process.

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